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Gynecological brachytherapy for postoperative endometrial cancer: dosimetric analysis (Ir-192 vs Co-60).
Tormo Ferrero, V; Duque Ugarte, R; Berenguer Francés, M Á; Cardenal Maciá, R.
Afiliação
  • Tormo Ferrero V; Radiotherapy Oncology Department, Hospital Universitari Sant Joan d´Alacant, Ctra. Nnal. 332 Alicante-Valencia, s/n, Sant Joan d´Alacant, 03550, Alicante, Spain. vicente.tormo@hotmail.com.
  • Duque Ugarte R; Radiotherapy Oncology Department, Hospital Universitari Sant Joan d´Alacant, Ctra. Nnal. 332 Alicante-Valencia, s/n, Sant Joan d´Alacant, 03550, Alicante, Spain.
  • Berenguer Francés MÁ; Radiotherapy Oncology Department, Hospital Universitari Sant Joan d´Alacant, Ctra. Nnal. 332 Alicante-Valencia, s/n, Sant Joan d´Alacant, 03550, Alicante, Spain.
  • Cardenal Maciá R; Radiotherapy Oncology Department, Hospital Universitari Sant Joan d´Alacant, Ctra. Nnal. 332 Alicante-Valencia, s/n, Sant Joan d´Alacant, 03550, Alicante, Spain.
Clin Transl Oncol ; 19(11): 1409-1413, 2017 Nov.
Article em En | MEDLINE | ID: mdl-28516398
INTRODUCTION: Endovaginal brachytherapy treatment dosimetry differences were studied using Ir-192 or Co-60 sources for postoperative endometrial cancer. MATERIALS AND METHODS: A prospective descriptive study was conducted. Thirty-six dosimetry plans of different patients were studied (15 by Ir-192 and 21 by Co-60). Variables studied included D2cc Rectum, D2cc Bladder, D2cc Sigmoid, dose percentage at point 0 (applicator surface on the top of the cylinder) and dose percentage at point 1 (5 mm deep on the top of the cylinder). A comparative analysis was performed of the values obtained from each variable between Ir-192 and Co-60 treatments. We compared average of each variables between Iridium and Cobalt by T Student for independent samples (SPSS 22). RESULTS: There were no significant differences on using Ir-192 or Co-60 by variables, except for dose percentage at point 1 in which we detected significant differences (Table 1). Table 1 The results Variables Sources Iridium 192 Cobalt 60 D2cc Rectum (mean dose) [rank] 6.01 Gy [3.99-7.90] 5.28 Gy [3.87-6,34] D2cc Bladder (mean dose) [rank] 5.82 Gy [4.20-8.38] 5.05 Gy [2.23-6.95] D2cc Sigmoid (mean dose) [rank] 4.43 Gy [1.66-6.67] 2.33 Gy [0.60-4.28] Dose percentage at point 0a (mean) [rank] 210.74% [120.90-234.90] 204.75% [177.10-223] Dose percentage at point 1b (mean) [rank] 93.49% [87.30-100.60] 100.11% [96.70-102] aPoint 0: point to the applicator surface bPoint 1: point to 5 mm applicator surface DISCUSSION: Brachytherapy treatment dosimetry plans are similar using Ir-192 or Co-60, except dose percentage at point 1. In the scientific literature, some differences exist and there are some advantages in using cobalt.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cuidados Pós-Operatórios / Planejamento da Radioterapia Assistida por Computador / Braquiterapia / Radioisótopos de Irídio / Neoplasias do Endométrio / Radioisótopos de Cobalto / Órgãos em Risco Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans Idioma: En Revista: Clin Transl Oncol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Espanha País de publicação: Itália
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cuidados Pós-Operatórios / Planejamento da Radioterapia Assistida por Computador / Braquiterapia / Radioisótopos de Irídio / Neoplasias do Endométrio / Radioisótopos de Cobalto / Órgãos em Risco Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans Idioma: En Revista: Clin Transl Oncol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Espanha País de publicação: Itália