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Stiff-Person Syndrome and Graves' Disease: A Pediatric Case Report.
Medeiros, Lais Moreira; Morais, Thulio Carvalho; Primo, Arlete Esteves Lopes; Speltri, Valeria Casella; Rocha, Maria Sheila Guimaraes.
Afiliação
  • Medeiros LM; Department of Neurology, Hospital Santa Marcelina, São Paulo, Brazil.
  • Morais TC; Department of Neurology, Hospital Santa Marcelina, São Paulo, Brazil.
  • Primo AEL; Department of Pediatrics, Hospital Santa Marcelina, São Paulo, Brazil.
  • Speltri VC; Department of Pediatrics, Hospital Santa Marcelina, São Paulo, Brazil.
  • Rocha MSG; Department of Neurology, Hospital Santa Marcelina, São Paulo, Brazil.
Child Neurol Open ; 3: 2329048X16684397, 2016.
Article em En | MEDLINE | ID: mdl-28503622
A 9-year-old female child presented with a history of falls, weight loss, diffuse leg pain, and progressive gait disorder, following 1 previous event described as a tonic-clonic seizure. She had increased thyroid volume, brisk symmetric reflexes, abnormal gait, and painful spasms of the paraspinal musculature. Thyroid function tests indicated biochemical hyperthyroidism, and thyrotropin receptor antibodies were positive. Her electromyography showed continuous activation of normal motor units of the paraspinal and proximal lower extremity muscles. The patient had a diagnosis of Graves' disease with associated stiff-person syndrome, with elevated anti-glutamic acid decarboxylase antibody levels. After intravenous immunoglobulin therapy, her ambulation was substantially improved and the symptoms of stiff-person syndrome decreased dramatically.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Child Neurol Open Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Child Neurol Open Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos