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Paraneoplastic neutrophilic leukocytosis syndrome in a cat with recurrent mammary carcinoma.
Jark, Paulo C; Raposo-Ferreira, Talita Mm; Terra, Erika M; Sierra Matiz, Oscar R; Anai, Letícia A; Fonseca-Alves, Carlos E; Tinucci-Costa, Mirela; Laufer-Amorim, Renee; De Nardi, Andrigo B.
Afiliação
  • Jark PC; Clinical Veterinary Department, College of Agricultural and Veterinary Sciences, São Paulo State University 'Júlio de Mesquita Filho' (UNESP), Jaboticabal, São Paulo, Brazil.
  • Raposo-Ferreira TM; Clinical Veterinary Department, College of Agricultural and Veterinary Sciences, São Paulo State University 'Júlio de Mesquita Filho' (UNESP), Jaboticabal, São Paulo, Brazil.
  • Terra EM; Clinical Veterinary Department, College of Agricultural and Veterinary Sciences, São Paulo State University 'Júlio de Mesquita Filho' (UNESP), Jaboticabal, São Paulo, Brazil.
  • Sierra Matiz OR; Clinical Veterinary Department, College of Agricultural and Veterinary Sciences, São Paulo State University 'Júlio de Mesquita Filho' (UNESP), Jaboticabal, São Paulo, Brazil.
  • Anai LA; Clinical Veterinary Department, College of Agricultural and Veterinary Sciences, São Paulo State University 'Júlio de Mesquita Filho' (UNESP), Jaboticabal, São Paulo, Brazil.
  • Fonseca-Alves CE; Pathology Veterinary Department, College of Veterinary and Zootechnical Medicine, São Paulo State University 'Júlio de Mesquita Filho' (UNESP), Botucatu, São Paulo, Brazil.
  • Tinucci-Costa M; Clinical Veterinary Department, College of Agricultural and Veterinary Sciences, São Paulo State University 'Júlio de Mesquita Filho' (UNESP), Jaboticabal, São Paulo, Brazil.
  • Laufer-Amorim R; Pathology Veterinary Department, College of Veterinary and Zootechnical Medicine, São Paulo State University 'Júlio de Mesquita Filho' (UNESP), Botucatu, São Paulo, Brazil.
  • De Nardi AB; Clinical Veterinary Department, College of Agricultural and Veterinary Sciences, São Paulo State University 'Júlio de Mesquita Filho' (UNESP), Jaboticabal, São Paulo, Brazil.
JFMS Open Rep ; 1(2): 2055116915608202, 2015.
Article em En | MEDLINE | ID: mdl-28491389
CASE SUMMARY: A spayed 12-year-old female domestic shorthair cat presented with nodular lesions on the ventral-right thoracic wall after complete mastectomy 4 months previously. The prior diagnosis was tubulopapillary mammary carcinoma with axillary lymph node metastasis, and a recurrence was confirmed. A gradual and sequential increase in the total number of leukocytes with severe neutrophilia (95.632/µl) developed over the course of the illness, along with an increase in the size of the recurrent mass. The severe leukocytosis did not show any response to antibiotic therapy, and no evidence of infection was observed. Bone marrow cytology confirmed hypercellularity in the myeloid cell lineage. Based on these findings, paraneoplastic neutrophilic leukocytosis syndrome was suspected. An incisional biopsy of the recurrent mass was consistent with recurrent tubulopapillary mammary carcinoma. Malignant epithelial cells stained positive upon immunohistochemistry for granulocyte-macrophage colony-stimulating factor, cytokeratin and vimentin. After the final diagnosis of paraneoplastic neutrophilic leukocytosis syndrome, the cat was euthanized at the owner's request. RELEVANCE AND NOVEL INFORMATION: This is a novel case of paraneoplastic leukocytosis syndrome associated with mammary carcinoma in a cat. Although there are some reports describing paraneoplastic leukocytosis in cats, the relationship between this syndrome and feline mammary tumors has not been described.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: JFMS Open Rep Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: JFMS Open Rep Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido