Strategies in 'snake venomics' aiming at an integrative view of compositional, functional, and immunological characteristics of venoms.
J Venom Anim Toxins Incl Trop Dis
; 23: 26, 2017.
Article
em En
| MEDLINE
| ID: mdl-28465677
This work offers a general overview on the evolving strategies for the proteomic analysis of snake venoms, and discusses how these may be combined through diverse experimental approaches with the goal of achieving a more comprehensive knowledge on the compositional, toxic, and immunological characteristics of venoms. Some recent developments in this field are summarized, highlighting how strategies have evolved from the mere cataloguing of venom components (proteomics/venomics), to a broader exploration of their immunological (antivenomics) and functional (toxicovenomics) characteristics. Altogether, the combination of these complementary strategies is helping to build a wider, more integrative view of the life-threatening protein cocktails produced by venomous snakes, responsible for thousands of deaths every year.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
J Venom Anim Toxins Incl Trop Dis
Ano de publicação:
2017
Tipo de documento:
Article
País de publicação:
Brasil