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Free leucine supplementation during an 8-week resistance training program does not increase muscle mass and strength in untrained young adult subjects.
Aguiar, Andreo Fernando; Grala, Alan Pablo; da Silva, Rubens Alexandre; Soares-Caldeira, Lúcio Flávio; Pacagnelli, Francis Lopes; Ribeiro, Alex Silva; da Silva, Douglas Kratki; de Andrade, Walquíria Batista; Balvedi, Mario Carlos Welin.
Afiliação
  • Aguiar AF; Center of Research in Health Sciences, North University of Paraná (UNOPAR), Avenue Paris, 675, Jardim Piza, Londrina, PR, 86041-120, Brazil. afaguiarunesp@gmail.com.
  • Grala AP; Center of Research in Health Sciences, North University of Paraná (UNOPAR), Avenue Paris, 675, Jardim Piza, Londrina, PR, 86041-120, Brazil.
  • da Silva RA; Center of Research in Health Sciences, North University of Paraná (UNOPAR), Avenue Paris, 675, Jardim Piza, Londrina, PR, 86041-120, Brazil.
  • Soares-Caldeira LF; Center of Research in Health Sciences, North University of Paraná (UNOPAR), Avenue Paris, 675, Jardim Piza, Londrina, PR, 86041-120, Brazil.
  • Pacagnelli FL; Department of Physiotherapy, University of Western São Paulo (UNOESTE), Presidente Prudente, São Paulo, Brazil.
  • Ribeiro AS; Center of Research in Health Sciences, North University of Paraná (UNOPAR), Avenue Paris, 675, Jardim Piza, Londrina, PR, 86041-120, Brazil.
  • da Silva DK; Center of Research in Health Sciences, North University of Paraná (UNOPAR), Avenue Paris, 675, Jardim Piza, Londrina, PR, 86041-120, Brazil.
  • de Andrade WB; Center of Research in Health Sciences, North University of Paraná (UNOPAR), Avenue Paris, 675, Jardim Piza, Londrina, PR, 86041-120, Brazil.
  • Balvedi MCW; Center of Research in Health Sciences, North University of Paraná (UNOPAR), Avenue Paris, 675, Jardim Piza, Londrina, PR, 86041-120, Brazil.
Amino Acids ; 49(7): 1255-1262, 2017 07.
Article em En | MEDLINE | ID: mdl-28444456
The purpose of this study was to examine the effects of free leucine supplementation on changes in skeletal muscle mass and strength during a resistance training (RT) program in previously untrained, young subjects. In a double-blind, randomized, placebo-controlled study, 20 healthy young (22 ± 2 years) participants were assigned to two groups: a placebo-supplement group (PLA, N = 10) or a leucine-supplement group (LEU, N = 10). Both groups underwent an 8-week hypertrophic RT program (2 days/week), consuming an equivalent amount of leucine (3.0 g/day in a single post-training dose) or placebo (cornstarch). Quadriceps muscle strength, cross-sectional area (CSA) of the vastus lateralis (VL), and rectus femoris (RF), as well as the habitual dietary intake were assessed before and after the 8-week intervention period. There was a similar improvement in muscle strength (Leg press, LEU: +33% vs. PLA: +37%; P > 0.05, and knee extension, LEU: +31% vs. PLA: 34%; P > 0.05) and CSA (VL, LEU: 8.9% vs. PLA: 9.6%; P > 0.05, and RF, LEU: +21.6% vs. PLA: + 16.4%; P > 0.05) in the both groups from pre- to post-training. In addition, there was no significant (P > 0.05) difference in daily dietary intake between the LEU and PLA groups before and after the intervention period. Free leucine supplementation (3.0 g/day post-training) does not increase muscle strength or CSA during RT in healthy young subjects consuming adequate dietary protein intake.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Resistência Física / Aptidão Física / Músculo Esquelético / Suplementos Nutricionais / Leucina Tipo de estudo: Clinical_trials / Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Adolescent / Adult / Female / Humans / Male Idioma: En Revista: Amino Acids Assunto da revista: BIOQUIMICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Brasil País de publicação: Áustria
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Resistência Física / Aptidão Física / Músculo Esquelético / Suplementos Nutricionais / Leucina Tipo de estudo: Clinical_trials / Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Adolescent / Adult / Female / Humans / Male Idioma: En Revista: Amino Acids Assunto da revista: BIOQUIMICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Brasil País de publicação: Áustria