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Treatment of One Case with Cryoglobulinaemia Secondary to Connective Tissue Disease with Small Doses of Rituximab.
Wang, X; Ning, Y; Wang, L; Zhang, J; Wang, Y; Shen, H.
Afiliação
  • Wang X; Department of Rheumatology, the Second Hospital of Lanzhou University, Lanzhou 730030, China.
  • Ning Y; Department of Nephropathy, the Second Hospital of Lanzhou University, Lanzhou 730030, China.
  • Wang L; Department of Rheumatology, the Second Hospital of Lanzhou University, Lanzhou 730030, China.
  • Zhang J; Department of Rheumatology, the Second Hospital of Lanzhou University, Lanzhou 730030, China.
  • Wang Y; Department of Rheumatology, the Second Hospital of Lanzhou University, Lanzhou 730030, China.
  • Shen H; Department of Rheumatology, the Second Hospital of Lanzhou University, Lanzhou 730030, China, e-mail: hailishencn@126.com.
West Indian Med J ; 65(2): 398-400, 2016 Apr 04.
Article em En | MEDLINE | ID: mdl-28358454
OBJECTIVE: This study aims to observe the clinical efficacy of low-dose rituximab in patients with cryoglobulinaemia secondary to connective tissue diseases. METHODS: Rituximab (100 mg) was infused in patients once a week for four weeks, combined with prednisone (20 mg) once a day, and reduced regularly. Treatment effect was observed regularly. RESULTS: Joint pain, fever, rash and fatigue symptoms in patients eased. The serology (globulin, erythrocyte sedimentation rate, C-reactive protein, lactate dehydrogenase and others) parameters returned to normal. CONCLUSION: Low-dose rituximab therapy for cryoglobulinaemia secondary to connective tissue diseases was safe and effective, and can be used as a treatment option in this condition.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: West Indian Med J Ano de publicação: 2016 Tipo de documento: Article País de afiliação: China País de publicação: Jamaica

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: West Indian Med J Ano de publicação: 2016 Tipo de documento: Article País de afiliação: China País de publicação: Jamaica