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A Randomized Controlled Trial of Procedural Techniques for Large Volume Paracentesis.
Shriver, Amy; Rudnick, Sean; Intagliata, Nicolas; Wang, Amanda; Caldwell, Stephen H; Northup, Patrick.
Afiliação
  • Shriver A; Division of Gastroenterology and Hepatology, University of Virginia, Charlottesville, Virginia, USA.
  • Rudnick S; Division of Gastroenterology and Hepatology, University of Virginia, Charlottesville, Virginia, USA.
  • Intagliata N; Division of Gastroenterology and Hepatology, University of Virginia, Charlottesville, Virginia, USA.
  • Wang A; University of Virginia School of Medicine, Charlottesville, Virginia, USA.
  • Caldwell SH; Division of Gastroenterology and Hepatology, University of Virginia, Charlottesville, Virginia, USA.
  • Northup P; Division of Gastroenterology and Hepatology, University of Virginia, Charlottesville, Virginia, USA.
Ann Hepatol ; 16(2): 279-284, 2017.
Article em En | MEDLINE | ID: mdl-28233752
INTRODUCTION: The aim of this study is to investigate large volume therapeutic paracentesis using either a z-tract or axial (coxial) technique in a randomized controlled trial. MATERIALS AND METHODS: In this randomized, single blind study, patients with cirrhosis undergoing outpatient therapeutic paracentesis were randomized to the z-tract or the modified angular (coaxial) needle insertion technique. Subject and procedure characteristics were compared between the groups with ascites leakage as quantified by need for dressing changes with standardized sized gauze pads as a primary endpoint and subject procedural discomfort, operator preference, and procedure complications as secondary endpoints. RESULTS: 72 paracenteses were performed during the study period: 34 to the z-tract and 38 to the coaxial insertion technique. Following exclusions, a total of 61 paracenteses were analyzed: 30 using the z-tract technique and 31 using the coaxial technique. There were equal rates of post-procedural leakage of ascites between groups (13% in both groups, p = 1.00). Using the visual analog scale (0 - 100), there was a statistically significant increase in the subject reported pain score with the z-tract compared with the coaxial method [26.4 (95% CI 18.7 - 34.1) vs. 17.2 (95% CI 10.6 - 23.8), p = 0.04]. Mean physician rated procedure difficulty (1 - 5) was significantly higher for the z-tract versus the coaxial technique [2.1 (95% CI 1.6 - 2.6) vs. 1.5 (95% CI 1.2 - 1.8), p = 0.04]. CONCLUSION: When compared to the z-tract technique, the coaxial insertion technique is superior during large volume paracentesis in cirrhosis patients.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ascite / Paracentese / Cirrose Hepática Tipo de estudo: Clinical_trials / Diagnostic_studies / Etiology_studies Limite: Female / Humans / Male / Middle aged País/Região como assunto: America do norte Idioma: En Revista: Ann Hepatol Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: México

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ascite / Paracentese / Cirrose Hepática Tipo de estudo: Clinical_trials / Diagnostic_studies / Etiology_studies Limite: Female / Humans / Male / Middle aged País/Região como assunto: America do norte Idioma: En Revista: Ann Hepatol Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: México