Changes in alpha-melanocyte-stimulating hormone content in discrete hypothalamic areas of the male rat during a twenty-four-hour period.
Horm Res
; 27(2): 78-83, 1987.
Article
em En
| MEDLINE
| ID: mdl-2820856
Circadian variations in alpha-melanocyte-stimulating hormone (alpha-MSH) content of discrete hypothalamic areas of the male rat were observed either with radioimmunoassay or bioassay. In the medial basal hypothalamus and preoptic area the alpha-MSH content increased sharply between 02.00 and 06.00 h, showing the highest concentration at 06.00 h. In contrast, no significant changes in alpha-MSH content were detected in the lateral hypothalamus during a 24-hour period. Pituitary alpha-MSH also showed a diurnal variation which was different from that in the two hypothalamic areas. The finding that alpha-MSH values in the brain are maximal during the activity period of the rat is in agreement with results demonstrating a role of alpha-MSH in behaviour and locomotor activity.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Alfa-MSH
/
Ritmo Circadiano
/
Hipotálamo
Limite:
Animals
Idioma:
En
Revista:
Horm Res
Ano de publicação:
1987
Tipo de documento:
Article
País de afiliação:
Argentina
País de publicação:
Suíça