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Prognostic role of margin status in open and CO2 laser cordectomy for T1a-T1b glottic cancer.
Landolfo, Vincenzo; Gervasio, Carmine Fernando; Riva, Giuseppe; Garzaro, Massimiliano; Audisio, Rita; Pecorari, Giancarlo; Albera, Roberto.
Afiliação
  • Landolfo V; University of Turin, Surgical Sciences Department, 1st ENT Division, Turin, Italy.
  • Gervasio CF; University of Turin, Surgical Sciences Department, 2nd ENT Division, Turin, Italy.
  • Riva G; University of Turin, Surgical Sciences Department, 1st ENT Division, Turin, Italy. Electronic address: giuseppe.riva84@gmail.com.
  • Garzaro M; University of Turin, Surgical Sciences Department, 1st ENT Division, Turin, Italy.
  • Audisio R; University of Turin, Surgical Sciences Department, 1st ENT Division, Turin, Italy.
  • Pecorari G; University of Turin, Surgical Sciences Department, 1st ENT Division, Turin, Italy.
  • Albera R; University of Turin, Surgical Sciences Department, 2nd ENT Division, Turin, Italy.
Braz J Otorhinolaryngol ; 2016 Dec 24.
Article em En | MEDLINE | ID: mdl-28110846
INTRODUCTION: Cordectomy by laringofissure and transoral laser surgery has been proposed for the treatment of early glottic cancer. OBJECTIVES: The aim of this retrospective study was to evaluate the prognostic value of margin status in 162 consecutive cases of early glottic carcinoma (Tis-T1) treated with CO2 laser endoscopic surgery (Group A) or laryngofissure cordectomy (Group B), and to compare the oncologic and functional results. METHODS: Clinical prognostic factors, local recurrence rate according to margin status, overall survival and disease-free survival were analyzed. RESULTS: Margin status is related to recurrence rate in both groups (p<0.05) without significant differences between open and laser cordectomy (p>0.05). The 5 years overall survival and disease-free survival were respectively 90.48% and 85.71% in Group A; 88.14% and 86.44% in Group B (p>0.05). Lower tracheostomy rate, earlier recovery of swallowing function and shorter hospital stay were observed in Group A (p<0.05). CONCLUSIONS: Margin status has a prognostic role in T1a-T1b glottic cancer. Transoral laser surgery showed similar oncologic results of open cordectomy, with better functional outcomes.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Observational_studies / Prognostic_studies Idioma: En Revista: Braz J Otorhinolaryngol Assunto da revista: OTORRINOLARINGOLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Itália País de publicação: Brasil
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Observational_studies / Prognostic_studies Idioma: En Revista: Braz J Otorhinolaryngol Assunto da revista: OTORRINOLARINGOLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Itália País de publicação: Brasil