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Isopropyl alcohol is as efficient as chlorhexidine to prevent contamination of blood cultures.
Martínez, Jovanna; Macías, Juan H; Arreguín, Virginia; Álvarez, Jose A; Macías, Alejandro E; Mosqueda-Gómez, Juan L.
Afiliação
  • Martínez J; Hospital Regional de Alta Especialidad del Bajío, León, Guanajuato, Mexico.
  • Macías JH; Universidad de Guanajuato, León, Guanajuato, Mexico.
  • Arreguín V; Antisepsia Central, León, Guanajuato, Mexico.
  • Álvarez JA; Hospital Regional de Alta Especialidad del Bajío, León, Guanajuato, Mexico; Universidad de Guanajuato, León, Guanajuato, Mexico.
  • Macías AE; Universidad de Guanajuato, León, Guanajuato, Mexico.
  • Mosqueda-Gómez JL; Universidad de Guanajuato, León, Guanajuato, Mexico; Centro Ambulatorio para la Prevención y Atención en SIDA e Infecciones de Trasmisión Sexual (CAPASITS), León, Guanajuato, Mexico. Electronic address: crc.jl.mosqueda@gmail.com.
Am J Infect Control ; 45(4): 350-353, 2017 Apr 01.
Article em En | MEDLINE | ID: mdl-28089672
BACKGROUND: False-positive blood cultures can lead to unnecessary risks and misuse of antibiotics; to reduce rates of false-positives, it would be useful to determine whether use of an antiseptic with a prolonged effect is required. METHODS: Clinical study of efficacy (blinded and randomized) to compare the rate of blood culture contamination when skin antisepsis was performed with 70% isopropyl alcohol or 2% chlorhexidine gluconate in 70% isopropyl alcohol in 2 hospitals. Patients aged 16 years or older with suspected bloodstream infection who were allocated in the emergency room, internal medicine ward, or intensive care unit were included. RESULTS: Five of 563 (0.9%) blood cultures from the isopropyl arm and 10 of 539 (1.9%) from the chlorhexidine arm were contaminated. No significant differences were observed among the rate of contamination (χ2=1.27; P = .3) or the relative risk of contamination (relative risk = 2.09; 95% confidence interval, 0.72-6.07; P = .2). CONCLUSIONS: The rates of blood contamination were not different when isopropyl alcohol and chlorhexidine were compared. Isopropyl alcohol could be used for skin antisepsis before blood collection.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Manejo de Espécimes / Clorexidina / Desinfecção / 2-Propanol / Hemocultura / Anti-Infecciosos Locais Tipo de estudo: Clinical_trials / Etiology_studies / Evaluation_studies Limite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Am J Infect Control Ano de publicação: 2017 Tipo de documento: Article País de afiliação: México País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Manejo de Espécimes / Clorexidina / Desinfecção / 2-Propanol / Hemocultura / Anti-Infecciosos Locais Tipo de estudo: Clinical_trials / Etiology_studies / Evaluation_studies Limite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Am J Infect Control Ano de publicação: 2017 Tipo de documento: Article País de afiliação: México País de publicação: Estados Unidos