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Amerindian (but not African or European) ancestry is significantly associated with diurnal preference within an admixed Brazilian population.
Egan, Kieren J; Campos Santos, Hadassa; Beijamini, Felipe; Duarte, Núbia E; Horimoto, Andréa R V R; Taporoski, Tâmara P; Vallada, Homero; Negrão, André B; Krieger, José E; Pedrazzoli, Mário; Knutson, Kristen L; Pereira, Alexandre C; von Schantz, Malcolm.
Afiliação
  • Egan KJ; a Faculty of Health and Medical Sciences , University of Surrey , Guildford , Surrey , UK.
  • Campos Santos H; b Laboratory of Genetics and Molecular Cardiology , Heart Institute (Incor), University of São Paulo Medical School , São Paulo , SP , Brazil.
  • Beijamini F; c Institute of Psychiatry , University of São Paulo Medical School , São Paulo , SP , Brazil.
  • Duarte NE; b Laboratory of Genetics and Molecular Cardiology , Heart Institute (Incor), University of São Paulo Medical School , São Paulo , SP , Brazil.
  • Horimoto AR; b Laboratory of Genetics and Molecular Cardiology , Heart Institute (Incor), University of São Paulo Medical School , São Paulo , SP , Brazil.
  • Taporoski TP; c Institute of Psychiatry , University of São Paulo Medical School , São Paulo , SP , Brazil.
  • Vallada H; c Institute of Psychiatry , University of São Paulo Medical School , São Paulo , SP , Brazil.
  • Negrão AB; b Laboratory of Genetics and Molecular Cardiology , Heart Institute (Incor), University of São Paulo Medical School , São Paulo , SP , Brazil.
  • Krieger JE; b Laboratory of Genetics and Molecular Cardiology , Heart Institute (Incor), University of São Paulo Medical School , São Paulo , SP , Brazil.
  • Pedrazzoli M; d School of Arts, Sciences, and Humanities , University of São Paulo , São Paulo , SP , Brazil.
  • Knutson KL; e Department of Medicine , University of Chicago , Chicago , IL , USA.
  • Pereira AC; b Laboratory of Genetics and Molecular Cardiology , Heart Institute (Incor), University of São Paulo Medical School , São Paulo , SP , Brazil.
  • von Schantz M; a Faculty of Health and Medical Sciences , University of Surrey , Guildford , Surrey , UK.
Chronobiol Int ; 34(2): 269-272, 2017.
Article em En | MEDLINE | ID: mdl-28055282
Significant questions remain unanswered regarding the genetic versus environmental contributions to racial/ethnic differences in sleep and circadian rhythms. We addressed this question by investigating the association between diurnal preference, using the morningness-eveningness questionnaire (MEQ), and genetic ancestry within the Baependi Heart Study cohort, a highly admixed Brazilian population based in a rural town. Analysis was performed using measures of ancestry, using the Admixture program, and MEQ from 1,453 individuals. We found an association between the degree of Amerindian (but not European of African) ancestry and morningness, equating to 0.16 units for each additional percent of Amerindian ancestry, after adjustment for age, sex, education, and residential zone. To our knowledge, this is the first published report identifying an association between genetic ancestry and MEQ, and above all, the first one based on ancestral contributions within individuals living in the same community. This previously unknown ancestral dimension of diurnal preference suggests a stratification between racial/ethnic groups in an as yet unknown number of genetic polymorphisms.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Indígenas Norte-Americanos / Ritmo Circadiano Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Aspecto: Patient_preference Limite: Adult / Female / Humans / Male / Middle aged País/Região como assunto: America do sul / Brasil Idioma: En Revista: Chronobiol Int Assunto da revista: FISIOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Indígenas Norte-Americanos / Ritmo Circadiano Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Aspecto: Patient_preference Limite: Adult / Female / Humans / Male / Middle aged País/Região como assunto: America do sul / Brasil Idioma: En Revista: Chronobiol Int Assunto da revista: FISIOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de publicação: Reino Unido