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Oral perineurioma: clinicopathologic features from two cases and review of literature.
Gomes da Silva, Wagner; Martínez, Marisol Martínez; Miranda, Águida Maria Menezes Aguiar; Silva, Roberto Bastos; da Silveira, Henrique Martins; de Almeida, Oslei Paes; Pires, Fábio Ramôa.
Afiliação
  • Gomes da Silva W; Oral Pathology, Piracicaba Dental School, University of Campinas, Piracicaba, Sao Paulo, Brazil.
  • Martínez MM; Oral Pathology, Piracicaba Dental School, University of Campinas, Piracicaba, Sao Paulo, Brazil.
  • Miranda ÁM; Stomatology Service, Brazilian Dental Association, Rio de Janeiro, Rio de Janeiro, Brazil.
  • Silva RB; Oral and Maxillofacial Surgery, State University of Rio de Janeiro, Rio de Janeiro, Brazil.
  • da Silveira HM; Oral and Maxillofacial Surgery, State University of Rio de Janeiro, Rio de Janeiro, Brazil.
  • de Almeida OP; Oral Pathology, Piracicaba Dental School, University of Campinas, Piracicaba, Sao Paulo, Brazil.
  • Pires FR; Stomatology Service, Brazilian Dental Association, Rio de Janeiro, Rio de Janeiro, Brazil; Oral Pathology, School of Dentistry, State University of Rio de Janeiro, Rio de Janeiro, Brazil. Electronic address: Ramoafop@yahoo.com.
Article em En | MEDLINE | ID: mdl-28034640
The present study reports two cases of oral perineuriomas, including a clinicopathologic review of the 39 published cases (17 intraneural and 22 extraneural perineuriomas) in the English language literature. In the first case, the tumor occurred in an 84-year-old male as a painless, asymptomatic, 20-mm submucosal nodule on the right lower mucobuccal fold near to the premolar area. In the second case, a 46-year-old female presented with a painless, 25-mm, slow-growing, fibrous, pedunculated nodule on the right buccal mucosa. In the first case, the tumor was composed of spindle cells arranged in a storiform pattern, classified as intraneural perineurioma; and in the second, it was an extraneural perineurioma, showing a whorled myxoid stroma. Immunohistochemical analysis confirmed the diagnosis by showing positivity for vimentin, EMA, and Glut-1 in case 1 and EMA, Glut-1, Claudin-1, and CD34 (focally) in case 2. Complete surgical removal was performed for both tumors, and there was no evidence of local recurrence after a long-term follow-up.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Bucais / Neoplasias de Bainha Neural / Mucosa Bucal Limite: Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Oral Surg Oral Med Oral Pathol Oral Radiol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Bucais / Neoplasias de Bainha Neural / Mucosa Bucal Limite: Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Oral Surg Oral Med Oral Pathol Oral Radiol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos