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Association of growth factor receptor-bound protein 10 gene polymorphism with superovulation traits in Changbaishan black cattle.
Wu, Y; Zhang, Z; Zhang, J B; Deng, Q.
Afiliação
  • Wu Y; Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Institute of Urology, Peking University Shenzhen Hospital, Shenzhen PKU-HKUST Medical Center, Shenzhen, China.
  • Zhang Z; Graduate School, Guangzhou Medical University, Guangzhou, China.
  • Zhang JB; Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Institute of Urology, Peking University Shenzhen Hospital, Shenzhen PKU-HKUST Medical Center, Shenzhen, China.
  • Deng Q; Graduate School, Anhui Medical University, Hefei, China.
Genet Mol Res ; 15(4)2016 Dec 19.
Article em En | MEDLINE | ID: mdl-28002603
The application of assisted reproductive technology in animal production benefits the economy and conservation of biological resources. Single nucleotide polymorphism (SNPs) was used as predictive markers for breeding and reproduction. In the present study, we examined the association between a SNP of the grb10 gene and superovulation traits in cattle. Sequencing results indicated a point mutation and statistical analysis showed a significant association of the mutation with superovulation traits. The high number of embryos collected from the heterozygotes suggested that the mutation in the grb10 gene exerted a significant effect on the number of embryos recovered although the quality was not affected. The grb10 gene may serve as a useful biomarker for donor selection.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Superovulação / Polimorfismo de Nucleotídeo Único / Locos de Características Quantitativas / Proteína Adaptadora GRB10 Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Revista: Genet Mol Res Assunto da revista: BIOLOGIA MOLECULAR / GENETICA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: China País de publicação: Brasil
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Superovulação / Polimorfismo de Nucleotídeo Único / Locos de Características Quantitativas / Proteína Adaptadora GRB10 Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Revista: Genet Mol Res Assunto da revista: BIOLOGIA MOLECULAR / GENETICA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: China País de publicação: Brasil