Your browser doesn't support javascript.
loading
Unraveling the Anticancer Effect of Curcumin and Resveratrol.
Pavan, Aline Renata; Silva, Gabriel Dalio Bernardes da; Jornada, Daniela Hartmann; Chiba, Diego Eidy; Fernandes, Guilherme Felipe Dos Santos; Man Chin, Chung; Dos Santos, Jean Leandro.
Afiliação
  • Pavan AR; School of Pharmaceutical Sciences, UNESP-Univ Estadual Paulista, Araraquara 14800903, Brazil. alinerenatapavan2004@yahoo.com.br.
  • Silva GD; School of Pharmaceutical Sciences, UNESP-Univ Estadual Paulista, Araraquara 14800903, Brazil. gabriel.dalio@hotmail.com.
  • Jornada DH; School of Pharmaceutical Sciences, UNESP-Univ Estadual Paulista, Araraquara 14800903, Brazil. daniela.hj@hotmail.com.
  • Chiba DE; School of Pharmaceutical Sciences, UNESP-Univ Estadual Paulista, Araraquara 14800903, Brazil. chiba.diego@outlook.com.
  • Fernandes GF; School of Pharmaceutical Sciences, UNESP-Univ Estadual Paulista, Araraquara 14800903, Brazil. guilhermefelipe@outlook.com.
  • Man Chin C; School of Pharmaceutical Sciences, UNESP-Univ Estadual Paulista, Araraquara 14800903, Brazil. chungmc@fcfar.unesp.br.
  • Dos Santos JL; School of Pharmaceutical Sciences, UNESP-Univ Estadual Paulista, Araraquara 14800903, Brazil. santosjl@fcfar.unesp.br.
Nutrients ; 8(11)2016 Nov 10.
Article em En | MEDLINE | ID: mdl-27834913
Resveratrol and curcumin are natural products with important therapeutic properties useful to treat several human diseases, including cancer. In the last years, the number of studies describing the effect of both polyphenols against cancer has increased; however, the mechanism of action in all of those cases is not completely comprehended. The unspecific effect and the ability to interfere in assays by both polyphenols make this challenge even more difficult. Herein, we analyzed the anticancer activity of resveratrol and curcumin reported in the literature in the last 11 years, in order to unravel the molecular mechanism of action of both compounds. Molecular targets and cellular pathways will be described. Furthermore, we also discussed the ability of these natural products act as chemopreventive and its use in association with other anticancer drugs.
Assuntos
Palavras-chave

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estilbenos / Curcumina / Neoplasias / Antineoplásicos Fitogênicos Limite: Animals / Humans Idioma: En Revista: Nutrients Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estilbenos / Curcumina / Neoplasias / Antineoplásicos Fitogênicos Limite: Animals / Humans Idioma: En Revista: Nutrients Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça