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Microcephaly in north-east Brazil: a retrospective study on neonates born between 2012 and 2015.
Soares de Araújo, Juliana Sousa; Regis, Cláudio Teixeira; Gomes, Renata Grigório Silva; Tavares, Thiago Ribeiro; Rocha Dos Santos, Cícera; Assunção, Patrícia Melo; Nóbrega, Renata Valéria; Pinto, Diana de Fátima Alves; Bezerra, Bruno Vinícius Dantas; Mattos, Sandra da Silva.
Afiliação
  • Soares de Araújo JS; The Heart Circle-Royal Portuguese Hospital, Av. Agamenon Magalhães 2760, Paissandu, Recife, Pernambuco, CEP 52010-902, Brazil .
  • Regis CT; The Heart Circle-Royal Portuguese Hospital, Av. Agamenon Magalhães 2760, Paissandu, Recife, Pernambuco, CEP 52010-902, Brazil .
  • Gomes RG; The Heart Circle-Royal Portuguese Hospital, Av. Agamenon Magalhães 2760, Paissandu, Recife, Pernambuco, CEP 52010-902, Brazil .
  • Tavares TR; The Heart Circle-Royal Portuguese Hospital, Av. Agamenon Magalhães 2760, Paissandu, Recife, Pernambuco, CEP 52010-902, Brazil .
  • Rocha Dos Santos C; The Heart Circle-Royal Portuguese Hospital, Av. Agamenon Magalhães 2760, Paissandu, Recife, Pernambuco, CEP 52010-902, Brazil .
  • Assunção PM; The Heart Circle-Royal Portuguese Hospital, Av. Agamenon Magalhães 2760, Paissandu, Recife, Pernambuco, CEP 52010-902, Brazil .
  • Nóbrega RV; The Heart Circle-Royal Portuguese Hospital, Av. Agamenon Magalhães 2760, Paissandu, Recife, Pernambuco, CEP 52010-902, Brazil .
  • Pinto DF; The Heart Circle-Royal Portuguese Hospital, Av. Agamenon Magalhães 2760, Paissandu, Recife, Pernambuco, CEP 52010-902, Brazil .
  • Bezerra BV; The Heart Circle-Royal Portuguese Hospital, Av. Agamenon Magalhães 2760, Paissandu, Recife, Pernambuco, CEP 52010-902, Brazil .
  • Mattos SD; The Heart Circle-Royal Portuguese Hospital, Av. Agamenon Magalhães 2760, Paissandu, Recife, Pernambuco, CEP 52010-902, Brazil .
Bull World Health Organ ; 94(11): 835-840, 2016 Nov 01.
Article em En | MEDLINE | ID: mdl-27821886
OBJECTIVE: To assess the number of children born with microcephaly in the State of Paraíba, north-east Brazil. METHODS: We contacted 21 maternity centres belonging to a paediatric cardiology network, with access to information regarding more than 100 000 neonates born between 1 January 2012 and 31 December 2015. For 10% of these neonates, nurses were requested to retrieve head circumference measurements data from delivery-room books. We used three separate criteria to classify whether a neonate had microcephaly: (i) the Brazilian Ministry of Health proposed criterion: term neonates (gestational age ≥ 37 weeks) with a head circumference of less than 32 cm; (ii) Fenton curves: neonates with a head circumference of less than -3 standard deviation for age and gender; or (iii) the proportionality criterion: neonates with a head circumference of less than ((height/2))+10) ± 2. FINDINGS: Between 1 and 31 December 2015, nurses obtained data for 16 208 neonates. Depending on which criterion we used, the number of neonates with microcephaly varied from 678 to 1272 (4.2-8.2%). Two per cent (316) of the neonates fulfilled all three criteria. We observed temporal fluctuations of microcephaly prevalence from late 2012. CONCLUSION: The numbers of microcephaly reported here are much higher than the 6.4 per 10 000 live births reported by the Brazilian live birth information system. The results raise questions about the notification system, the appropriateness of the diagnostic criteria and future implications for the affected children and their families. More studies are needed to understand the epidemiology and the implications for the Brazilian health system.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Microcefalia Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Female / Humans / Male / Newborn País/Região como assunto: America do sul / Brasil Idioma: En Revista: Bull World Health Organ Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Microcefalia Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Female / Humans / Male / Newborn País/Região como assunto: America do sul / Brasil Idioma: En Revista: Bull World Health Organ Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça