Your browser doesn't support javascript.
loading
Freeze-all cycle for all normal responders?
Roque, Matheus; Valle, Marcello; Guimarães, Fernando; Sampaio, Marcos; Geber, Selmo.
Afiliação
  • Roque M; ORIGEN-Center for Reproductive Medicine, Avenida Rodolfo de Amoedo, 140-Barra da Tijuca, Rio de Janeiro, Brazil. matheusroque@hotmail.com.
  • Valle M; Universidade Federal de Minas Gerais, Avenida Alfredo Balena, 190, Belo Horizonte, Brazil. matheusroque@hotmail.com.
  • Guimarães F; ORIGEN-Center for Reproductive Medicine, Avenida Rodolfo de Amoedo, 140-Barra da Tijuca, Rio de Janeiro, Brazil.
  • Sampaio M; ORIGEN-Center for Reproductive Medicine, Avenida Rodolfo de Amoedo, 140-Barra da Tijuca, Rio de Janeiro, Brazil.
  • Geber S; ORIGEN-Center for Reproductive Medicine, Av do Contorno, 7747-Lourdes, Belo Horizonte, Brazil.
J Assist Reprod Genet ; 34(2): 179-185, 2017 Feb.
Article em En | MEDLINE | ID: mdl-27817036
PURPOSE: The purpose of this study is to evaluate the freeze-all strategy in subgroups of normal responders, to assess whether this strategy is beneficial regardless of ovarian response, and to evaluate the possibility of implementing an individualized embryo transfer (iET) based on ovarian response. METHODS: This was an observational, cohort study performed in a private IVF center. A total of 938 IVF cycles were included in this study. The patients were submitted to controlled ovarian stimulation (COS) with a gonadotropin-releasing hormone (GnRH) antagonist protocol and a cleavage-stage day 3 embryo transfer. We performed a comparison of outcomes between the fresh embryo transfer (n = 523) and the freeze-all cycles (n = 415). The analysis was performed in two subgroups of patients based on the number of retrieved oocytes: Group 1 (4-9 oocytes) and Group 2 (10-15 oocytes). RESULT(S): In Group 1 (4-9 retrieved oocytes), the implantation rates (IR) were 17.9 and 20.5% (P = 0.259) in the fresh and freeze-all group, respectively; the ongoing pregnancy rates (OPR) were 31 and 33% (P = 0.577) in the fresh and freeze-all group, respectively. In Group 2 (10-15 oocytes), the IR were 22.1 and 30.1% (P = 0.028) and the OPR were 34 and 47% (P = 0.021) in the fresh and freeze-all groups, respectively. CONCLUSION(S): Although the freeze-all policy may be related to better in vitro fertilization (IVF) outcomes in normal responders, these potential advantages decrease with worsening ovarian response. Patients with poorer ovarian response do not benefit from the freeze-all strategy.
Assuntos
Palavras-chave
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oócitos / Fertilização in vitro / Criopreservação / Transferência Embrionária Tipo de estudo: Observational_studies Limite: Adult / Female / Humans / Pregnancy Idioma: En Revista: J Assist Reprod Genet Assunto da revista: GENETICA / MEDICINA REPRODUTIVA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Brasil País de publicação: Holanda
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oócitos / Fertilização in vitro / Criopreservação / Transferência Embrionária Tipo de estudo: Observational_studies Limite: Adult / Female / Humans / Pregnancy Idioma: En Revista: J Assist Reprod Genet Assunto da revista: GENETICA / MEDICINA REPRODUTIVA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Brasil País de publicação: Holanda