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Combinations of drugs in the Treatment of Obesity.
Halpern, Bruno; Oliveira, Eduardo S L; Faria, André M; Halpern, Alfredo; Melo, Maria Edna de; Cercato, Cintia; Mancini, Marcio C.
Afiliação
  • Halpern B; Obesity & Metabolic Syndrome Group, Discipline of Endocrinology & Metabolism, Hospital das Clínicas, Faculty of Medicine, University of São Paulo, Av. Dr. Enéas de Carvalho Aguiar, 255, 7º andar, sala 7037, 05403-000 - São Paulo, SP, Brazil. brunohalpern@hotmail.com.
  • Oliveira ES; Obesity & Metabolic Syndrome Group, Discipline of Endocrinology & Metabolism, Hospital das Clínicas, Faculty of Medicine, University of São Paulo, Av. Dr. Enéas de Carvalho Aguiar, 255, 7º andar, sala 7037, 05403-000 - São Paulo, SP, Brazil. eduardolorena@uol.com.br.
  • Faria AM; Obesity & Metabolic Syndrome Group, Discipline of Endocrinology & Metabolism, Hospital das Clínicas, Faculty of Medicine, University of São Paulo, Av. Dr. Enéas de Carvalho Aguiar, 255, 7º andar, sala 7037, 05403-000 - São Paulo, SP, Brazil. andremfaria@hotmail.com.
  • Halpern A; Obesity & Metabolic Syndrome Group, Discipline of Endocrinology & Metabolism, Hospital das Clínicas, Faculty of Medicine, University of São Paulo, Av. Dr. Enéas de Carvalho Aguiar, 255, 7º andar, sala 7037, 05403-000 - São Paulo, SP, Brazil. alfredo.halpern@netpoint.com.br.
  • Melo ME; Laboratory of Carbohydrates and Radioimuneassay/LIM-18, Faculty of Medicine, University of São Paulo, Av. Dr Arnaldo, 455 01246-903 - São Paulo, SP, Brazil. medna@usp.br.
  • Cercato C; Obesity & Metabolic Syndrome Group, Discipline of Endocrinology & Metabolism, Hospital das Clínicas, Faculty of Medicine, University of São Paulo, Av. Dr. Enéas de Carvalho Aguiar, 255, 7º andar, sala 7037, 05403-000 - São Paulo, SP, Brazil. ccercato@netpoint.com.br.
  • Mancini MC; Laboratory of Carbohydrates and Radioimuneassay/LIM-18, Faculty of Medicine, University of São Paulo, Av. Dr Arnaldo, 455 01246-903 - São Paulo, SP, Brazil. mmancini@usp.br.
Pharmaceuticals (Basel) ; 3(8): 2398-2415, 2010 Jul 27.
Article em En | MEDLINE | ID: mdl-27713360
Obesity is a chronic disease associated with excess morbidity and mortality. Clinical treatment, however, currently offers disappointing results, with very high rates of weight loss failure or weight regain cycles, and only two drugs (orlistat and sibutramine) approved for long-term use. Drugs combinations can be an option for its treatment but, although widely used in clinical practice, very few data are available in literature for its validation. Our review focuses on the rationale for their use, with advantages and disadvantages; on combinations often used, with or without studies; and on new perspectives of combinations being studied mainly by the pharmaceutical industry.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Pharmaceuticals (Basel) Ano de publicação: 2010 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Pharmaceuticals (Basel) Ano de publicação: 2010 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça