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Indigenous Ethnicity and Low Maternal Education Are Associated with Delayed Diagnosis and Mortality in Infants with Congenital Heart Defects in Panama.
Castro, Franz; Zúñiga, Julio; Higuera, Gladys; Carrión Donderis, María; Gómez, Beatriz; Motta, Jorge.
Afiliação
  • Castro F; Department of Research and Health Technology Assessment, Instituto Conmemorativo Gorgas de Estudios de la Salud, Panama City, Panama.
  • Zúñiga J; Department of Research and Health Technology Assessment, Instituto Conmemorativo Gorgas de Estudios de la Salud, Panama City, Panama.
  • Higuera G; Department of Research and Health Technology Assessment, Instituto Conmemorativo Gorgas de Estudios de la Salud, Panama City, Panama.
  • Carrión Donderis M; Department of Research and Health Technology Assessment, Instituto Conmemorativo Gorgas de Estudios de la Salud, Panama City, Panama.
  • Gómez B; Department of Research and Health Technology Assessment, Instituto Conmemorativo Gorgas de Estudios de la Salud, Panama City, Panama.
  • Motta J; Department of Research and Health Technology Assessment, Instituto Conmemorativo Gorgas de Estudios de la Salud, Panama City, Panama.
PLoS One ; 11(9): e0163168, 2016.
Article em En | MEDLINE | ID: mdl-27648568
BACKGROUND: This is the first study in Panama and Central America that has included indigenous populations in an assessment of the association between socioeconomic variables with delayed diagnosis and mortality due to congenital heart defects (CHD). METHODS: A retrospective observational study was conducted. A sample calculation was performed and 954 infants born from 2010 to 2014 were randomly selected from clinical records of all Panamanian public health institutions with paediatric cardiologists. Critical CHD was defined according to the defects listed as targets of newborn pulse oximetry screening. Diagnoses were considered delayed when made after the third day of life for the critical CHD and after the twentieth day of life for the non-critical. A logistic regression model was performed to examine the association between socioeconomic variables and delayed diagnosis. A Cox proportional hazards model was used to assess the relationship between socioeconomic features and mortality. RESULTS: An increased risk of delayed diagnosis was observed in infants with indigenous ethnicity (AOR, 1.56; 95% CI, 1.03-2.37), low maternal education (AOR, 1.57; 95% CI, 1.09-2.25) and homebirth (AOR, 4.32; 95% CI, 1.63-11.48). Indigenous infants had a higher risk of dying due to CHD (HR, 1.43; 95% CI, 1.03-1.99), as did those with low maternal education (HR, 1.95; 95% CI, 1.45-2.62). CONCLUSION: Inequalities in access to health care, conditioned by unfavourable socioeconomic features, may play a key role in delayed diagnosis and mortality of CHD patients. Further studies are required to study the relationship between indigenous ethnicity and these adverse health outcomes.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Indígenas Sul-Americanos / Escolaridade / Diagnóstico Tardio / Cardiopatias Congênitas Tipo de estudo: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Aspecto: Determinantes_sociais_saude Limite: Humans / Infant / Newborn País/Região como assunto: America central / Panama Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Panamá País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Indígenas Sul-Americanos / Escolaridade / Diagnóstico Tardio / Cardiopatias Congênitas Tipo de estudo: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Aspecto: Determinantes_sociais_saude Limite: Humans / Infant / Newborn País/Região como assunto: America central / Panama Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Panamá País de publicação: Estados Unidos