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[Creutzfeldt-Jakob disease: Report of one case]. / Desafíos en el diagnóstico de enfermedad de Creutzfeldt-Jakob: Caso clínico.
Ramírez, Marcos; Gallardo, Andrés; Vidal, Aarón; Cornejo, Sebastián; Ramírez, Darío; Medinas, Danilo; Bustamante, Gonzalo; Pasquali, Renzo; Hetz, Claudio.
Afiliação
  • Ramírez M; Departamento de Ciencias Neurológicas Oriente, Facultad de Medicina, Universidad de Chile, Santiago, Chile, marcosirp@hotmail.com.
  • Gallardo A; Departamento de Ciencias Neurológicas Oriente, Facultad de Medicina, Universidad de Chile, Santiago, Chile.
  • Vidal A; Instituto de Neurocirugía Dr. Asenjo, Santiago, Chile.
  • Cornejo S; Escuela de Postgrado, Universidad de Santiago de Chile, Santiago, Chile.
  • Ramírez D; Servicio de Neurología, Hospital del Salvador, Santiago, Chile.
  • Medinas D; Biomedical Neuroscience Institute, Facultad de Medicina, Universidad de Chile, Santiago, Chile.
  • Bustamante G; Servicio de Neurología, Hospital del Salvador, Santiago, Chile.
  • Pasquali R; Departamento de Ciencias Neurológicas Oriente, Facultad de Medicina, Universidad de Chile, Santiago, Chile.
  • Hetz C; Biomedical Neuroscience Institute, Facultad de Medicina, Universidad de Chile, Santiago, Chile.
Rev Med Chil ; 144(6): 796-806, 2016 Jun.
Article em Es | MEDLINE | ID: mdl-27598501
Creutzfeldt-Jakob disease has a higher incidence in Chile than in other countries. The post mortem pathological characterization of brain tissue is necessary to reach a definitive diagnosis. We report a 73 years old man with a history compatible with of a rapidly progressive dementia, in which the first electroencephalographic study showed a pattern consistent with non-convulsive status epilepticus. Besides discarding this diagnosis, it was necessary to rule out other causes of rapidly progressive dementia such as Hashimoto encephalopathy. Finally, the sustained clinical deterioration with no response to anticonvulsants and corticosteroids, the imaging studies, a serial electroencephalographic monitoring study and the detection of 14-3-3 protein in cerebrospinal fluid were the keys to achieve the diagnosis of the disease.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Síndrome de Creutzfeldt-Jakob Tipo de estudo: Diagnostic_studies Limite: Aged / Humans / Male Idioma: Es Revista: Rev Med Chil Ano de publicação: 2016 Tipo de documento: Article País de publicação: Chile
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Síndrome de Creutzfeldt-Jakob Tipo de estudo: Diagnostic_studies Limite: Aged / Humans / Male Idioma: Es Revista: Rev Med Chil Ano de publicação: 2016 Tipo de documento: Article País de publicação: Chile