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Selenium Status in Patients with Turner Syndrome: a Biochemical Assessment Related with Body Composition.
Pires, Liliane Viana; Siviero-Miachon, Adriana Aparecida; Spinola-Castro, Angela Maria; Pimentel, José Alexandre Coelho; Nishimura, Luciana Sigueta; Maia, Carla Soraya Costa; Cozzolino, Silvia Maria Franciscato.
Afiliação
  • Pires LV; Department of Food and Experimental Nutrition, Faculty of Pharmaceutical Sciences, University of São Paulo, Av. Professor Lineu Prestes, n°580, Cidade Universitária, São Paulo, SP, 05508-900, Brazil. lvianapires@gmail.com.
  • Siviero-Miachon AA; Division of Pediatric Endocrinology, Department of Pediatrics, Federal University of São Paulo, São Paulo, Brazil.
  • Spinola-Castro AM; Division of Pediatric Endocrinology, Department of Pediatrics, Federal University of São Paulo, São Paulo, Brazil.
  • Pimentel JA; Department of Food and Experimental Nutrition, Faculty of Pharmaceutical Sciences, University of São Paulo, Av. Professor Lineu Prestes, n°580, Cidade Universitária, São Paulo, SP, 05508-900, Brazil.
  • Nishimura LS; Department of Food and Experimental Nutrition, Faculty of Pharmaceutical Sciences, University of São Paulo, Av. Professor Lineu Prestes, n°580, Cidade Universitária, São Paulo, SP, 05508-900, Brazil.
  • Maia CS; Department of Nutrition, State University of Ceara, Ceara, Brazil.
  • Cozzolino SM; Department of Food and Experimental Nutrition, Faculty of Pharmaceutical Sciences, University of São Paulo, Av. Professor Lineu Prestes, n°580, Cidade Universitária, São Paulo, SP, 05508-900, Brazil.
Biol Trace Elem Res ; 176(2): 217-224, 2017 Apr.
Article em En | MEDLINE | ID: mdl-27565799
Studies about selenium status in patients with Turner syndrome (TS) are non-existent in the literature. The aim of this study was to evaluate selenium status in patients with TS, while considering the different ages of the studied population and the relation with body composition. In total, 33 patients with TS were evaluated and grouped according to their developmental stages (children, adolescents, and adults). Selenium concentrations in their plasma, erythrocytes, urine, and nails were determined by using hydride generation atomic absorption spectrometry and erythrocyte glutathione peroxidase activity were measured by using Randox commercial kits. Additionally, height, weight, body fat percentage, waist circumference, and waist-height ratio were measured to characterize the patients. No differences in the selenium concentrations in the plasma, erythrocyte, urine, and nails or in the glutathione peroxidase activity were observed among the age groups (p > 0.05). The evaluated selenium levels were less than the established normal ones. The patients with larger waist circumference, body fat percentage, body mass index, and waist-height ratio showed lower glutathione peroxidase enzyme activity (p = 0.023). The present study shows that most patients with TS are deficient in selenium and that those with a greater accumulation of body fat have a lower GPx activity.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Selênio / Síndrome de Turner Limite: Adolescent / Adult / Child / Humans Idioma: En Revista: Biol Trace Elem Res Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Selênio / Síndrome de Turner Limite: Adolescent / Adult / Child / Humans Idioma: En Revista: Biol Trace Elem Res Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos