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Bioprosthetic mesh of bacterial cellulose for treatment of abdominal muscle aponeurotic defect in rat model.
Silveira, Raquel Kelner; Coelho, Antônio Roberto Barros; Pinto, Flávia Cristina Morone; de Albuquerque, Amanda Vasconcelos; de Melo Filho, Djalma Agripino; de Andrade Aguiar, José Lamartine.
Afiliação
  • Silveira RK; Department of Surgery, Center for Health Sciences, Federal University of Pernambuco, UFPE, R. Major João Ribeiro Pinheiro, N. 245, Apt. 310, Edf. São Paulo, Recife, Pernambuco, CEP 50-740-170, Brazil.
  • Coelho AR; Department of Surgery, Center for Health Sciences, Federal University of Pernambuco, UFPE, R. Major João Ribeiro Pinheiro, N. 245, Apt. 310, Edf. São Paulo, Recife, Pernambuco, CEP 50-740-170, Brazil.
  • Pinto FC; Center for Experimental Surgery, Department of Surgery, Center for Health Sciences, Federal University of Pernambuco, UFPE, Recife, Pernambuco, Brazil.
  • de Albuquerque AV; Center for Experimental Surgery, Department of Surgery, Center for Health Sciences, Federal University of Pernambuco, UFPE, Recife, Pernambuco, Brazil. amandabiocel@gmail.com.
  • de Melo Filho DA; Department of Surgery, Center for Health Sciences, Federal University of Pernambuco, UFPE, R. Major João Ribeiro Pinheiro, N. 245, Apt. 310, Edf. São Paulo, Recife, Pernambuco, CEP 50-740-170, Brazil.
  • de Andrade Aguiar JL; Department of Surgery, Center for Health Sciences, Federal University of Pernambuco, UFPE, R. Major João Ribeiro Pinheiro, N. 245, Apt. 310, Edf. São Paulo, Recife, Pernambuco, CEP 50-740-170, Brazil.
J Mater Sci Mater Med ; 27(8): 129, 2016 Aug.
Article em En | MEDLINE | ID: mdl-27379627
The use of meshes for treatment of hernias continues to draw attention of surgeons and the industry in the search of an ideal prosthesis. The purpose of this work is to use meshes manufactured from bacterial cellulose, evaluate their organic tissue interaction and compare with an expanded polytetrafluorethylene (ePTFE's) prosthesis used to repair acute defect of muscle aponeurotic induced in rats. Forty-five male Wistar rats were classified using the following criteria: (1) surgical repair of acute muscle aponeurotic defect with perforated bacterial cellulose film (PBC; n = 18); (2) compact bacterial cellulose film (CBC; n = 12) and (3) ePTFE; (n = 15). After postoperative period, rectangles (2 × 3 cm) including prosthesis, muscles and peritoneum were collected for biomechanical, histological and stereological analysis. In all cases, the maximum acceptable error probability for rejecting the null hypothesis was 5 %. Between PBC and CBC samples, the variables of strain (P = 0.011) and elasticity (P = 0.035) were statistically different. The same was found between CBC and ePTFE (elasticity, P = 0.000; strain, P = 0.009). PBC differed from CBC for giant cells (P = 0.001) and new blood vessels (P = 0.000). In conclusion, there was biological integration and biomechanical elasticity of PBC; therefore, we think this option should be considered as a new alternative biomaterial for use as a bio prosthesis.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Politetrafluoretileno / Telas Cirúrgicas / Celulose / Aderências Teciduais / Músculos Abdominais / Hérnia Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: J Mater Sci Mater Med Assunto da revista: ENGENHARIA BIOMEDICA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Politetrafluoretileno / Telas Cirúrgicas / Celulose / Aderências Teciduais / Músculos Abdominais / Hérnia Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: J Mater Sci Mater Med Assunto da revista: ENGENHARIA BIOMEDICA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos