Fast analysis of terbutaline in pharmaceuticals using multi-walled nanotubes modified electrodes from recordable compact disc.
Anal Chim Acta
; 928: 32-38, 2016 Jul 20.
Article
em En
| MEDLINE
| ID: mdl-27251854
In this study, homemade disposable gold electrodes made from recordable compact disks were modified with carbon nanotubes for amperometric quantification of terbutaline sulfate in pharmaceutical products. A flow cell using an impingent jet of solution on the electrode surface was build and used for amperometric detection, and a series of experiments were carried out to find the best experimental conditions for the new electrode in a specially designed cell. A linear response for terbutaline was obtained in the range from 3.0 × 10(-6) to 5.0 × 10(-4) mol L(-1) (at 0.63 V vs. Ag/AgCl). The limits of detection and quantification were calculated as 5.8 × 10(-7) mol L(-1) (S/N = 3) and 1.9 × 10(-6) mol L(-1) (S/N = 10), respectively. A frequency of 30 injections h(-1) was attained. The proposed method was successfully applied to the analyses of commercial syrup samples, and all results were in good agreement with those obtained by using high performance liquid chromatography and capillary electrophoresis-tandem mass spectrometry.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Terbutalina
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Preparações Farmacêuticas
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Discos Compactos
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Nanotubos de Carbono
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Eletroquímica
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Limite de Detecção
Idioma:
En
Revista:
Anal Chim Acta
Ano de publicação:
2016
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Holanda