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 Liver transplantation followed by autologous stem cell transplantation for acute liver failure caused by AL amyloidosis. Case report and review of the literature.
Elnegouly, Mayada; Specht, Katja; Zoller, Heinz; Matevossian, Edouard; Bassermann, Florian; Umgelter, Andreas.
Afiliação
  • Elnegouly M; 2nd Medical Department, Klinikum rechts der Isar, Technische Universität München, Germany and Kasr Alainy Hospital, Department of Infectious Diseases and Endemic Hepatology and Gastroenterology, Cairo University, Cairo, Egypt.
  • Specht K; Institute of Pathology, § Department of Surgery, || 3rd Medical Department, ¶ 2nd Medical Department. Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
  • Zoller H; Universitätsklinik für Innere Medizin II, Universität Innsbruck, Innsbruck, Austria.
  • Matevossian E; Department of Surgery Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
  • Bassermann F; Universität Innsbruck, Innsbruck, Austria.
  • Umgelter A; 2nd Medical Department. Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
Ann Hepatol ; 15(4): 592-7, 2016.
Article em En | MEDLINE | ID: mdl-27236160
 Hepatic involvement in AL amyloidosis may present as acute liver failure. Historically, liver transplantation in these cases has achieved poor outcomes due to progress of amyloidosis and non-hepatic organ damage. In the era of bortezomib treatment, the prognosis of AL amyloidosis has been markedly improved and may also result in better post-transplant outcomes. We present a case of isolated acute liver failure caused by AL amyloidosis, bridged to transplantation with bortezomib and treated with sequential orthotopic liver transplantation (OLT) and autologous stem cell transplantation. The patient is in stable remission 3 years after OLT.
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transplante de Fígado / Falência Hepática Aguda / Transplante de Células-Tronco de Sangue Periférico / Bortezomib / Amiloidose / Antineoplásicos Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Humans / Male / Middle aged Idioma: En Revista: Ann Hepatol Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Egito País de publicação: México
Buscar no Google
Adicionar na Minha BVS
Imprimir
XML
PubMed Links

Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transplante de Fígado / Falência Hepática Aguda / Transplante de Células-Tronco de Sangue Periférico / Bortezomib / Amiloidose / Antineoplásicos Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Humans / Male / Middle aged Idioma: En Revista: Ann Hepatol Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Egito País de publicação: México