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Association of severe haemophilia A and factor V Leiden: report of three cases.
Arruda, V R; Annichino-Bizzacchi, J M; Antunes, S V; Costa, F F.
Afiliação
  • Arruda VR; Haematology-Haemotherapy Centre, State University of Campinas, UNICAMP, Campinas, and Department of Internal Medicine, School of Medicine, Escola Paulista de Medicina, Säo Paulo, Brazil Valder R. Arruda, M.D., Ph.D., Haematology-Haemotherapy Centre, UNICAMP, CP 6198, CEP 13.081-970, Campinas, SP, Br
  • Annichino-Bizzacchi JM; Haematology-Haemotherapy Centre, State University of Campinas, UNICAMP, Campinas, and Department of Internal Medicine, School of Medicine, Escola Paulista de Medicina, Säo Paulo, Brazil Valder R. Arruda, M.D., Ph.D., Haematology-Haemotherapy Centre, UNICAMP, CP 6198, CEP 13.081-970, Campinas, SP, Br
  • Antunes SV; Haematology-Haemotherapy Centre, State University of Campinas, UNICAMP, Campinas, and Department of Internal Medicine, School of Medicine, Escola Paulista de Medicina, Säo Paulo, Brazil Valder R. Arruda, M.D., Ph.D., Haematology-Haemotherapy Centre, UNICAMP, CP 6198, CEP 13.081-970, Campinas, SP, Br
  • Costa FF; Haematology-Haemotherapy Centre, State University of Campinas, UNICAMP, Campinas, and Department of Internal Medicine, School of Medicine, Escola Paulista de Medicina, Säo Paulo, Brazil Valder R. Arruda, M.D., Ph.D., Haematology-Haemotherapy Centre, UNICAMP, CP 6198, CEP 13.081-970, Campinas, SP, Br
Haemophilia ; 2(1): 51-3, 1996 Jan.
Article em En | MEDLINE | ID: mdl-27213907
The clinical severity of haemophilia is usually related to residual clotting factor activity. Reports of factor V deficiency or protein C have been described in haemophilic patients and both are involved in the activated protein C pathway. Recently, the poor response to activated protein C due to factor V Leiden (FQ506) has been associated with an increased risk of thrombosis and its incidence in the normal population is given as 2-7%. We describe three cases of severe haemophilia A heterozygous for factor V Leiden and its influence on phenotype.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Risk_factors_studies Idioma: En Revista: Haemophilia Assunto da revista: HEMATOLOGIA Ano de publicação: 1996 Tipo de documento: Article País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Risk_factors_studies Idioma: En Revista: Haemophilia Assunto da revista: HEMATOLOGIA Ano de publicação: 1996 Tipo de documento: Article País de publicação: Reino Unido