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Relation between Liver Transaminases and Dyslipidaemia among 2-10 y.o. Northern Mexican Children.
Bibiloni, Maria Del Mar; Salas, Rogelio; Nuñez, Georgina M; Villarreal, Jesús Z; Sureda, Antoni; Tur, Josep A.
Afiliação
  • Bibiloni Mdel M; Research Group on Community Nutrition and Oxidative Stress, University of Balearic Islands, E-07122, Palma de Mallorca, Spain.
  • Salas R; CIBEROBN (Physiopathology of Obesity and Nutrition), Instituto de Salud Carlos III, E-28029, Madrid, Spain.
  • Nuñez GM; Faculty of Public Health Nutrition, Autonomous University of Nuevo León, 64460, Monterrey, Mexico.
  • Villarreal JZ; Faculty of Public Health Nutrition, Autonomous University of Nuevo León, 64460, Monterrey, Mexico.
  • Sureda A; Department of Health of the State of Nuevo León, 64000, Monterrey, Mexico.
  • Tur JA; Research Group on Community Nutrition and Oxidative Stress, University of Balearic Islands, E-07122, Palma de Mallorca, Spain.
PLoS One ; 11(5): e0155994, 2016.
Article em En | MEDLINE | ID: mdl-27203747
BACKGROUND AND AIMS: The increase in overweight and obese children may be linked to increased rates of liver damage and dyslipidaemia. This study aimed to explore the associations of liver biomarkers with overweight/obesity and dyslipidaemia in Mexican children. METHODS: The study was a population-based cross-sectional nutritional survey carried out in the State of Nuevo León, Mexico. The study included a 414 subjects aged between 2 and 10 years old (47.8% girls) who took part in the State Survey of Nutrition and Health-Nuevo León 2011/2012. Associations between alanine aminotransferase (ALT) and aspartate aminotransferase (AST), ALT/AST ratio, and major components of serum lipid profile were assessed. RESULTS: Children with high ALT (defined as ≥P75) showed higher prevalence of dyslipidaemia than their counterparts, with high prevalence of high TChol (P = 0.053), non-HDL-chol, TG, and low HDL-chol. Children with an AST/ALT ≥T3 ratio were 0.43-times (95% CI: 0.25-0.74) and 0.27-times (95% CI: 0.17-0.44) low likely to be overweight/obese and to have dyslipidaemia than those with an AST/ALT
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dislipidemias / Fígado Tipo de estudo: Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Child / Child, preschool / Humans País/Região como assunto: Mexico Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Espanha País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dislipidemias / Fígado Tipo de estudo: Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Child / Child, preschool / Humans País/Região como assunto: Mexico Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Espanha País de publicação: Estados Unidos