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Random-start controlled ovarian stimulation for emergency fertility preservation in a patient with myelodysplastic syndrome: a case report.
Cai, H; Shen, H.
Afiliação
  • Cai H; Reproductive Medical Center, Peking University People's Hospital, Beijing, China.
  • Shen H; Reproductive Medical Center, Peking University People's Hospital, Beijing, China.
Braz J Med Biol Res ; 49(6): e5227, 2016.
Article em En | MEDLINE | ID: mdl-27191608
This study reports a case of a gonadotropin-releasing hormone agonist trigger in a young female with myelodysplastic syndrome (MDS) who underwent fertility preservation using random-start controlled ovarian stimulation. This method involves the stimulation of the ovary regardless of a patient's menstrual-cycle phase. A review of the related literature is also provided. A 17-year-old patient was diagnosed with MDS and required initiation of peripheral blood stem cell transplantation within a maximum of 3 weeks and was in the luteal phase of the menstrual cycle when the possibility of attempting preservation of fertility was presented to her. She opted for a random-start controlled ovarian stimulation with gonadotropins. With successful hemorrhagic prophylaxis, 17 oocytes were retrieved including 10 mature and 7 immature oocytes. Of the immature oocytes, 3 were successfully matured in vitro and a vitrification protocol was used to freeze the 13 mature oocytes.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Indução da Ovulação / Síndromes Mielodisplásicas / Preservação da Fertilidade Tipo de estudo: Clinical_trials / Guideline Limite: Adolescent / Female / Humans Idioma: En Revista: Braz J Med Biol Res Ano de publicação: 2016 Tipo de documento: Article País de afiliação: China País de publicação: Brasil

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Indução da Ovulação / Síndromes Mielodisplásicas / Preservação da Fertilidade Tipo de estudo: Clinical_trials / Guideline Limite: Adolescent / Female / Humans Idioma: En Revista: Braz J Med Biol Res Ano de publicação: 2016 Tipo de documento: Article País de afiliação: China País de publicação: Brasil