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Clinical effects of an avocado-soybean unsaponifiable extract on arthralgia and osteoarthritis of the temporomandibular joint: preliminary study.
Catunda, I S; Vasconcelos, B C do E; Andrade, E S de S; Costa, D F N.
Afiliação
  • Catunda IS; Department of Oral and Maxillofacial Surgery, University of Pernambuco, Recife, Pernambuco, Brazil.
  • Vasconcelos BC; Department of Oral and Maxillofacial Surgery, University of Pernambuco, Recife, Pernambuco, Brazil. Electronic address: belmiro@pesquisador.cnpq.br.
  • Andrade ES; Oral Pathology, University of Pernambuco, Recife, Pernambuco, Brazil.
  • Costa DF; Division of Oral and Maxillofacial Surgery, Restauração Hospital, Recife, Pernambuco, Brazil.
Int J Oral Maxillofac Surg ; 45(8): 1015-22, 2016 Aug.
Article em En | MEDLINE | ID: mdl-27026059
The aim of the present preliminary study was to investigate the effectiveness of an avocado-soybean unsaponifiable extract (ASU) in patients with arthralgia and osteoarthritis of the temporomandibular joint (TMJ). A randomized, double-blind, placebo-controlled trial was carried out. Fourteen women diagnosed with arthralgia and osteoarthritis of the TMJ using the Research Diagnostic Criteria for Temporomandibular Disorders were included in the statistical analysis. The women were allocated randomly to two groups: ASU group and placebo group. Pain was measured using a visual analogue scale and pressure algometer. Mandibular function was evaluated through measurement of mandibular movements. Quality of life was measured using the Oral Health Impact Profile (OHIP-14). The medication (ASU capsules or placebo capsules) was used for 4 months and the total follow-up was 6 months. Those taking the ASU extract had a decrease in pain symptoms and an improvement in quality of life. Moreover, a significant reduction in the use of rescue medication was found in the ASU group compared to the placebo group. This preliminary study provides strong evidence of the effectiveness of an avocado-soybean unsaponifiable extract in patients with degenerative joint diseases and arthralgia in the TMJ. Further studies with larger samples should be performed.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoartrite / Glycine max / Extratos Vegetais / Transtornos da Articulação Temporomandibular / Artralgia / Persea Tipo de estudo: Clinical_trials / Observational_studies Aspecto: Patient_preference Limite: Adult / Female / Humans Idioma: En Revista: Int J Oral Maxillofac Surg Assunto da revista: ODONTOLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Brasil País de publicação: Dinamarca
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoartrite / Glycine max / Extratos Vegetais / Transtornos da Articulação Temporomandibular / Artralgia / Persea Tipo de estudo: Clinical_trials / Observational_studies Aspecto: Patient_preference Limite: Adult / Female / Humans Idioma: En Revista: Int J Oral Maxillofac Surg Assunto da revista: ODONTOLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Brasil País de publicação: Dinamarca