Models of Inflammation: Carrageenan Air Pouch.
Curr Protoc Pharmacol
; 72: 5.6.1-5.6.9, 2016 Mar 18.
Article
em En
| MEDLINE
| ID: mdl-26995549
The subcutaneous air pouch is an in vivo model that can be used to study the components of acute and chronic inflammation, the resolution of the inflammatory response, the oxidative stress response, and potential therapeutic targets for treating inflammation. Injection of irritants into an air pouch in rats or mice induces an inflammatory response that can be quantified by the volume of exudate produced, the infiltration of cells, and the release of inflammatory mediators. The model presented in this unit has been extensively used to identify potential anti-inflammatory drugs.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pele
/
Carragenina
/
Mediadores da Inflamação
/
Inflamação
Limite:
Animals
Idioma:
En
Revista:
Curr Protoc Pharmacol
Ano de publicação:
2016
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Estados Unidos