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A comparison of two different doses of morphine added to spinal bupivacaine for inguinal hernia repair.
Meco, Basak Ceyda; Bermede, Onat; Vural, Cagil; Cakmak, Atil; Alanoglu, Zekeriyya; Alkis, Neslihan.
Afiliação
  • Meco BC; Department of Anesthesiology and Intensive Care, Ankara University Medical Faculty, Ankara, Turkey. Electronic address: basakceyda@hotmail.com.
  • Bermede O; Department of Anesthesiology and Intensive Care, Ankara University Medical Faculty, Ankara, Turkey.
  • Vural C; Department of Anesthesiology and Intensive Care, Ankara University Medical Faculty, Ankara, Turkey.
  • Cakmak A; Department of General Surgery, Ankara University Medical Faculty, Ankara, Turkey.
  • Alanoglu Z; Department of Anesthesiology and Intensive Care, Ankara University Medical Faculty, Ankara, Turkey.
  • Alkis N; Department of Anesthesiology and Intensive Care, Ankara University Medical Faculty, Ankara, Turkey.
Braz J Anesthesiol ; 66(2): 140-4, 2016.
Article em En | MEDLINE | ID: mdl-26952221
BACKGROUND AND OBJECTIVES: The aim of this study was to compare the effects of two different doses of intrathecal morphine on postoperative analgesia, postoperative first mobilization and urination times and the severity of side effects. METHODS: After Institutional Ethical Committee approval, 48 ASA I-II patients were enrolled in this randomized double-blinded study. Spinal anesthesia was performed with 0.1mg (Group I, n=22) or 0.4mg (Group II, n=26) ITM in addition to 7.5mg heavy bupivacaine. The first analgesic requirement, first mobilization and voiding times, and postoperative side effects were recorded. Statistical analyses were performed using SPSS 15.0 and p<0.05 was considered as statistically significant. The numeric data were analyzed by the t-test and presented as mean±SD. Categorical data were analyzed with the chi-square test and expressed as number of patients and percentage. RESULTS: Demographic data were similar among groups. There were no differences related to postoperative pain, first analgesic requirements, and first mobilization and first voiding times. The only difference between two groups was the vomiting incidence. In Group II 23% (n=6) of the patients had vomiting during the first postoperative 24h compared to 0% in Group I (p=0.025). CONCLUSION: For inguinal hernia repairs, the dose of 0.1mg of ITM provides comparable postoperative analgesia with a dose of 0.4mg, with significantly lower vomiting incidence when combined with low dose heavy bupivacaine.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bupivacaína / Hérnia Inguinal / Raquianestesia / Morfina Tipo de estudo: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies Aspecto: Ethics Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Braz J Anesthesiol Ano de publicação: 2016 Tipo de documento: Article País de publicação: Brasil
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bupivacaína / Hérnia Inguinal / Raquianestesia / Morfina Tipo de estudo: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies Aspecto: Ethics Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Braz J Anesthesiol Ano de publicação: 2016 Tipo de documento: Article País de publicação: Brasil