Your browser doesn't support javascript.
loading
Serum interleukin -8 is not a reliable marker for prediction of vesicoureteral reflux in children with febrile urinary tract infection.
Mahyar, Abolfazl; Ayazi, Parviz; Yarigarravesh, Mohammad Hadi; Khoeiniha, Mohammad Hossein; Oveisi, Sonia; Sahmani, Ahmad Ali; Esmaeily, Shiva.
Afiliação
  • Mahyar A; Department of Pediatrics, Qazvin Children hospital, Qazvin University of Medical Sciences, Qazvin, Iran.
  • Ayazi P; Department of Pediatrics, Qazvin Children hospital, Qazvin University of Medical Sciences, Qazvin, Iran.
  • Yarigarravesh MH; Department of Pediatrics, Qazvin Children hospital, Qazvin University of Medical Sciences, Qazvin, Iran.
  • Khoeiniha MH; Qazvin Children hospital, Qazvin University of Medical Sciences, Qazvin, Iran.
  • Oveisi S; Diseases Research Center, Qazvin University of Medical Sciences, Qazvin, Iran.
  • Sahmani AA; Laboratory department of Qazvin Children hospital, Qazvin University of Medical Sciences, Qazvin, Iran.
  • Esmaeily S; Department of statistics, Qazvin University of Medical Sciences, Qazvin, Iran.
Int Braz J Urol ; 41(6): 1160-6, 2015.
Article em En | MEDLINE | ID: mdl-26742975
OBJECTIVE: In view of the side effects of voiding cystourethrography (VCUG), identification of noninvasive markers predicting the presence of vesicoureteral reflux (VUR) is important. This study was conducted to determine the predictive value of serum interleukin-8 (IL-8) in diagnosis of VUR in children with first febrile urinary tract infection (UTI). MATERIALS AND METHODS: Eighty children with first febrile UTI were divided into two groups, with and without VUR, based on the results of VCUG .The sensitivity, specificity, positive and negative predictive value positive and negative likelihood ratio, and accuracy of IL-8 for prediction of VUR were investigated. RESULTS: Of the 80 children with febrile UTI, 30 (37.5%) had VUR. There was no significant difference between the children with and without VUR and also between low and high-grade VUR groups in terms of serum concentration of IL-8 (P>0.05). Based on ROC curve, the sensitivity, specificity, likelihood ratio positive, and accuracy of serum IL-8 was lower than those of erythrocyte sedimentation rate and C-reactive protein. Multivariate logistic regression analysis showed significant positive correlation only between erythrocyte sedimentation rate and VUR. CONCLUSIONS: This study showed no significant difference between the children with and without VUR in terms of the serum concentration of IL-8. Therefore, it seems that serum IL-8 is not a reliable marker for prediction of VUR.
Assuntos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções Urinárias / Refluxo Vesicoureteral / Interleucina-8 / Febre Tipo de estudo: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limite: Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: Int Braz J Urol Assunto da revista: UROLOGIA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Irã País de publicação: Brasil
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções Urinárias / Refluxo Vesicoureteral / Interleucina-8 / Febre Tipo de estudo: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limite: Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: Int Braz J Urol Assunto da revista: UROLOGIA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Irã País de publicação: Brasil