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Endovascular Treatment of Very Small Intracranial Aneurysms: Meta-Analysis.
Yamaki, V N; Brinjikji, W; Murad, M H; Lanzino, G.
Afiliação
  • Yamaki VN; From the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Foundation (V.N.Y.), Ministry of Education of Brazil, Brasilia, Brazil.
  • Brinjikji W; Department of Radiology (W.B.) brinjikji.waleed@mayo.edu.
  • Murad MH; Center for Science of Healthcare Delivery (M.H.M.).
  • Lanzino G; Department of Neurosurgery (G.L.), Mayo Clinic, Rochester, Minnesota.
AJNR Am J Neuroradiol ; 37(5): 862-7, 2016 May.
Article em En | MEDLINE | ID: mdl-26721770
BACKGROUND AND PURPOSE: Outcomes of endovascular treatment of very small intracranial aneurysms are still not well-characterized. Recently, several series assessing coil embolization of tiny aneurysms have presented new promising results. Thus, we performed a systematic review and meta-analysis of studies evaluating endovascular treatment of very small intracranial aneurysms. MATERIALS AND METHODS: We conducted a computerized search of Scopus, Medline, and the Web of Science for studies on endovascular treatment of very small (≤3 mm in diameter) intracranial aneurysms published between January 1996 and May 2015. Using a random-effects model, we evaluated clinical and angiographic outcomes. RESULTS: Twenty-two studies with 1105 tiny aneurysms (844 ruptured and 261 unruptured) endovascularly treated were included. Postoperative and long-term complete occlusion was achieved in 85% (95% CI, 78%-90%) and 91% (95% CI, 87%-94%) of aneurysms, respectively. The recanalization rate was 6% (95% CI, 4%-11%) and retreatment occurred in 7% (95% CI, 5%-9%) of cases. Seventy-nine percent (95% CI, 64%-89%) of patients had good neurologic outcome at long-term follow-up. Intraprocedural rupture occurred in 7% (95% CI, 5%-9%) of the coiling procedures, while thromboembolic complications occurred in 4% (95% CI, 3%-6%). CONCLUSIONS: Coil embolization of very small intracranial aneurysms can be performed safely and effectively. In the case of unruptured aneurysms, procedure-related complications are not negligible. Patients and providers should consider such risks when engaged in a shared decision-making process.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Aneurisma Intracraniano / Procedimentos Neurocirúrgicos / Embolização Terapêutica / Procedimentos Endovasculares Tipo de estudo: Prognostic_studies / Systematic_reviews Limite: Humans Idioma: En Revista: AJNR Am J Neuroradiol Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Aneurisma Intracraniano / Procedimentos Neurocirúrgicos / Embolização Terapêutica / Procedimentos Endovasculares Tipo de estudo: Prognostic_studies / Systematic_reviews Limite: Humans Idioma: En Revista: AJNR Am J Neuroradiol Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos