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RhD negativity among pregnant women in multiethnic Suriname.
Zonneveld, Rens; Schmitz, Peter; Eppink, Jedda; Mac Donald, M Sigrid; Nahar-van Venrooij, Lenny M W; Kanhai, Humphrey H H; Zijlmans, Wilco C W R.
Afiliação
  • Zonneveld R; Scientific Research Center Suriname, Academic Hospital Paramaribo, Paramaribo, Suriname.
  • Schmitz P; Department of Pediatrics, Academic Hospital Paramaribo, Paramaribo, Suriname.
  • Eppink J; Faculty of Medicine, Radboud University, Nijmegen, the Netherlands.
  • Mac Donald MS; Faculty of Medicine, Radboud University, Nijmegen, the Netherlands.
  • Nahar-van Venrooij LM; Scientific Research Center Suriname, Academic Hospital Paramaribo, Paramaribo, Suriname.
  • Kanhai HH; Scientific Research Center Suriname, Academic Hospital Paramaribo, Paramaribo, Suriname.
  • Zijlmans WC; Department of Public Health, Faculty of Medical Sciences, Paramaribo, Suriname.
Transfusion ; 56(2): 321-4, 2016 Feb.
Article em En | MEDLINE | ID: mdl-26677093
BACKGROUND: RhD negativity is distributed unevenly among different ethnicities. In this study we explored the frequencies of RhD negativity in pregnant women in multiethnic Suriname, along with screening results for red blood cell (RBC) antibodies in these women and their offspring. Results may help identify women at risk for hemolytic disease of the fetus and newborn. STUDY DESIGN AND METHODS: A retrospective study was performed in pregnant women who delivered at three major hospitals in Suriname between January 1, 2013, and December 31, 2014. RESULTS: The overall prevalences of RhD negativity among 8686 women was 4.3%. The percentages of RhD negativity in Maroons, Creoles, and Hindustani women were 7.2, 5.4, and 3.7%, respectively. Chinese and Javanese women had very low prevalences of 0.8 and 0.5%, respectively, and Amerindians showed no RhD negativity. Antibody screening was positive in six D- (five Maroons and one Creole) women and weakly positive in three women (two Creoles and one Maroon), making overall antibody prevalence 4.4%. In 15 (5.5%; 10 Maroons, four Creoles, one Chinese) newborns from D- mothers antibody screening was positive. CONCLUSION: In the multiethnic Surinamese population RhD negativity among pregnant women varied between 0.0 and 7.2% between ethnic groups. RBC antibodies were detected during pregnancy and in newborns in 4.4 and 5.5%, respectively.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sistema do Grupo Sanguíneo Rh-Hr / Gravidez / Isoanticorpos Tipo de estudo: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans País/Região como assunto: America do sul / Caribe ingles / Suriname Idioma: En Revista: Transfusion Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Suriname País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sistema do Grupo Sanguíneo Rh-Hr / Gravidez / Isoanticorpos Tipo de estudo: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans País/Região como assunto: America do sul / Caribe ingles / Suriname Idioma: En Revista: Transfusion Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Suriname País de publicação: Estados Unidos