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Acute lymphoblastic leukemia presenting with bilateral serous macular detachment.
Vieira, Luisa; Silva, Nuno Aguiar; Medeiros, Marco Dutra; Flores, Rita; Maduro, Vitor.
Afiliação
  • Vieira L; Central Lisbon Hospital Center, Lisbon, Portugal.
  • Silva NA; Central Lisbon Hospital Center, Lisbon, Portugal.
  • Medeiros MD; Central Lisbon Hospital Center, Lisbon, Portugal.
  • Flores R; Central Lisbon Hospital Center, Lisbon, Portugal.
  • Maduro V; Central Lisbon Hospital Center, Lisbon, Portugal.
Arq Bras Oftalmol ; 78(6): 382-4, 2015.
Article em En | MEDLINE | ID: mdl-26677044
Acute lymphoblastic leukemia is a malignant hematopoietic neoplasia, which is rare in adults. Although ocular fundus alterations may be commonly observed in the course of the disease, such alterations are rarely the presenting signs of the disease. Here we describe the case of a patient with painless and progressive loss of visual acuity (right eye, 2/10; left eye, 3/10) developing over two weeks, accompanied by fever and cervical lymphadenopathy. Fundus examination showed bilateral macular serous detachment, which was confirmed by optical coherence tomography. Fluorescein angiography revealed hyperfluorescent pinpoints in the posterior poles. The limits of the macular detachment were revealed in the late phase of the angiogram. The results of blood count analysis triggered a thorough, systematic patient examination. The diagnosis of acute lymphoblastic leukemia B (CD10+) was established, and intensive systemic chemotherapy was immediately initiated. One year after the diagnosis, the patient remains in complete remission without any ophthalmologic alterations.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Descolamento Retiniano / Leucemia-Linfoma Linfoblástico de Células Precursoras Limite: Female / Humans / Middle aged Idioma: En Revista: Arq Bras Oftalmol Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Portugal País de publicação: Brasil

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Descolamento Retiniano / Leucemia-Linfoma Linfoblástico de Células Precursoras Limite: Female / Humans / Middle aged Idioma: En Revista: Arq Bras Oftalmol Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Portugal País de publicação: Brasil