Changes in fatty acid composition associated with differentiation of Trypanosoma cruzi.

Esteves, M G; Gonzales-Perdomo, M; Alviano, C S; Angluster, J; Goldenberg, S

Esteves, M G; Gonzales-Perdomo, M; Alviano, C S; Angluster, J; Goldenberg, S.

Afiliação

Esteves MG; Instituto de Microbiologia, UFRJ, Cidade Universitaria, Rio de Janeiro, Brasil.

FEMS Microbiol Lett ; 50(1-2): 31-4, 1989 May.

Article em En | MEDLINE | ID: mdl-2661320

RESUMO

The fatty acid composition during the transformation of Trypanosoma cruzi epimastigotes into metacyclic trypomastigotes (metacyclogenesis) was analysed by gas-liquid chromatography and mass spectrometry. Significant qualitative and quantitative changes in the fatty acid composition occurred during incubation of epimastigotes derived from LIT medium in the triatomine artificial urine (TAU). Metacyclogenesis was also followed by alterations in the fatty acid pattern but these were considerably less pronounced when compared to the pattern obtained for TAU-incubated epimastigotes. These results suggest that changes in the lipid composition precede the morphological transformation of epimastigotes into metacyclic trypomastigotes.

Assuntos

Ácidos Graxos/análise; Trypanosoma cruzi/análise; Animais; Diferenciação Celular; Trypanosoma cruzi/fisiologia

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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Trypanosoma cruzi / Ácidos Graxos Tipo de estudo: Qualitative_research / Risk_factors_studies Limite: Animals Idioma: En Revista: FEMS Microbiol Lett Ano de publicação: 1989 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido

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