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Obstetric and Neonatal Adversities, Parity, and Tourette Syndrome: A Nationwide Registry.
Leivonen, Susanna; Voutilainen, Arja; Chudal, Roshan; Suominen, Auli; Gissler, Mika; Sourander, Andre.
Afiliação
  • Leivonen S; Department of Child Psychiatry, University of Turku, Turku, Finland; Child Neurology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland. Electronic address: susanna.leivonen@utu.fi.
  • Voutilainen A; Child Neurology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
  • Chudal R; Department of Child Psychiatry, University of Turku, Turku, Finland.
  • Suominen A; Department of Child Psychiatry, University of Turku, Turku, Finland.
  • Gissler M; National Institute of Health and Welfare (THL), Helsinki, Finland; Nordic School of Public Health, Gothenburg, Sweden.
  • Sourander A; Department of Child Psychiatry, University of Turku, Turku, Finland; Department of Child Psychiatry, Turku University Hospital, Turku, Finland; Regional Centre for Child and Youth Mental Health and Child Welfare, UiT The Arctic University of Norway, Tromsø, Norway.
J Pediatr ; 171: 213-9, 2016 Apr.
Article em En | MEDLINE | ID: mdl-26608088
OBJECTIVE: To determine the relationships between parity, obstetric adversities, neonatal factors, and Tourette syndrome in a large nationwide cohort. STUDY DESIGN: This nationwide, register-based, nested case-control study identified all children diagnosed with Tourette syndrome born between 1991 and 2010 from the Finnish Hospital Discharge Register (n = 767). Each case was matched to 4 controls. Information on parity, obstetric, and neonatal factors was obtained from the Finnish Medical Birth Register. Conditional logistic regression was used to determine the relationship between parity, obstetric, and neonatal factors, and Tourette syndrome. RESULTS: Nulliparity was associated with increased odds for Tourette syndrome (OR 1.7, 95% CI 1.4-2.2), and 3 or more previous births was associated with decreased odds for Tourette syndrome (OR 0.5, 95% CI 0.3-0.9) compared with parity 1-2. Birth weight 4000-4499 g was associated with decreased odds for Tourette syndrome (OR 0.7, 95% CI 0.5-0.9). Low birth weight, gestational age, weight for gestational age, Apgar score at 1 minute, induced labor, birth type or presentation, neonatal treatment, or maternal blood pressure were not associated with Tourette syndrome. CONCLUSIONS: Increasing parity and high birth weight are associated with decreased odds for Tourette syndrome.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Complicações na Gravidez / Síndrome de Tourette Tipo de estudo: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Newborn / Pregnancy País/Região como assunto: Europa Idioma: En Revista: J Pediatr Ano de publicação: 2016 Tipo de documento: Article País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Complicações na Gravidez / Síndrome de Tourette Tipo de estudo: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Newborn / Pregnancy País/Região como assunto: Europa Idioma: En Revista: J Pediatr Ano de publicação: 2016 Tipo de documento: Article País de publicação: Estados Unidos