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RELATED FACTORS FOR COLONIZATION BY Candida SPECIES IN THE ORAL CAVITY OF HIV-INFECTED INDIVIDUALS.
Menezes, Ralciane de Paula; Borges, Aércio Sebastião; Araujo, Lúcio Borges de; Pedroso, Reginaldo dos Santos; Röder, Denise Von Dolinger de Brito.
Afiliação
  • Menezes Rde P; Faculdade de Medicina Uberlândia, Universidade Federal de Uberlândia, Uberlândia, MG, Brasil.
  • Borges AS; Faculdade de Medicina, Universidade Federal de Uberlândia, Uberlândia, MG, Brasil.
  • Araujo LB; Faculdade de Matemática, Universidade Federal de Uberlândia, Uberlândia, MG, Brasil.
  • Pedroso Rdos S; Faculdade de Medicina Uberlândia, Universidade Federal de Uberlândia, Uberlândia, MG, Brasil.
  • Röder DV; Faculdade de Medicina Uberlândia, Universidade Federal de Uberlândia, Uberlândia, MG, Brasil.
Rev Inst Med Trop Sao Paulo ; 57(5): 413-9, 2015.
Article em En | MEDLINE | ID: mdl-26603229
UNLABELLED: The colonization of the oral cavity is a prerequisite to the development of oropharyngeal candidiasis. AIMS: The aims of this study were: to evaluate colonization and quantify Candida spp. in the oral cavity; to determine the predisposing factors for colonization; and to correlate the levels of CD4+ cells and viral load with the yeast count of colony forming units per milliliter (CFU/mL) in HIV-positive individuals treated at a University Hospital. Saliva samples were collected from 147 HIV patients and were plated on Sabouraud Dextrose Agar (SDA) and chromogenic agar, and incubated at 30 ºC for 72 h. Colonies with similar morphology in both media were counted and the result expressed in CFU/mL. RESULTS: Of the 147 HIV patients, 89 had positive cultures for Candida spp., with a total of 111 isolates, of which C. albicans was the most frequent species (67.6%), and the mean of colonies counted was 8.8 × 10³ CFU/mL. The main predisposing factors for oral colonization by Candida spp. were the use of antibiotics and oral prostheses. The use of reverse transcriptase inhibitors appears to have a greater protective effect for colonization. A low CD4+ T lymphocyte count is associated with a higher density of yeast in the saliva of HIV patients.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Saliva / Candida / Candidíase Bucal / Infecções Oportunistas Relacionadas com a AIDS Tipo de estudo: Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Rev Inst Med Trop Sao Paulo Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Saliva / Candida / Candidíase Bucal / Infecções Oportunistas Relacionadas com a AIDS Tipo de estudo: Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Rev Inst Med Trop Sao Paulo Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil