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Clinical guideline seom: hereditary colorectal cancer.
Guillén-Ponce, C; Serrano, R; Sánchez-Heras, A B; Teulé, A; Chirivella, I; Martín, T; Martínez, E; Morales, R; Robles, L.
Afiliação
  • Guillén-Ponce C; Medical Oncology Department, Hospital Universitario Ramón y Cajal, Carretera de Colmenar Viejo, KM 9,100, 28034, Madrid, Spain. carmenguillenponce@gmail.com.
  • Serrano R; Medical Oncology Department, Hospital Reina Sofía, Córdoba, Spain.
  • Sánchez-Heras AB; Medical Oncology Department, Hospital General Universitario de Elche, Elche (Alicante), Spain.
  • Teulé A; Medical Oncology Department, Instituto Catalán de Oncología (ICO), Barcelona, Spain.
  • Chirivella I; Medical Oncology Department, Hospital Clínico Universitario de Valencia, Valencia, Spain.
  • Martín T; Medical Oncology Department, Hospital Universitario de Salamanca, Salamanca, Spain.
  • Martínez E; Medical Oncology Department, Hospital Marqués de Valdecilla, Santander, Spain.
  • Morales R; Medical Oncology Department, Hospital La Mancha Centro, Alcázar De San Juan (Ciudad Real), Spain.
  • Robles L; Medical Oncology Department, Hospital Doce de Octubre, Madrid, Spain.
Clin Transl Oncol ; 17(12): 962-71, 2015 Dec.
Article em En | MEDLINE | ID: mdl-26586118
Genetic mutations have been identified as the cause of inherited cancer risk in some colon cancer; these mutations are estimated to account for only 5-6 % of colorectal cancer (CRC) cases overall. Up to 25-30 % of patients have a family history of CRC that suggests a hereditary component, common exposures among family members, or a combination of both. Cancers in people with a hereditary predisposition typically occur at an earlier age than in sporadic cases. A predisposition to CRC may include a predisposition to other cancers, such as endometrial cancer. We describe genetics, current diagnosis and management of CRC hereditary syndromes pointing to a multidisciplinary approach to achieve the best results in patients and family outcomes.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais Hereditárias sem Polipose / Guias de Prática Clínica como Assunto / Predisposição Genética para Doença Tipo de estudo: Diagnostic_studies / Guideline / Prognostic_studies / Screening_studies Limite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male / Middle aged / Newborn Idioma: En Revista: Clin Transl Oncol Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Espanha País de publicação: Itália
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais Hereditárias sem Polipose / Guias de Prática Clínica como Assunto / Predisposição Genética para Doença Tipo de estudo: Diagnostic_studies / Guideline / Prognostic_studies / Screening_studies Limite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male / Middle aged / Newborn Idioma: En Revista: Clin Transl Oncol Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Espanha País de publicação: Itália