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Innate Immune Factors in Mothers' Breast Milk and Their Lack of Association With Rotavirus Vaccine Immunogenicity in Nicaraguan Infants.
Becker-Dreps, Sylvia; Choi, Wan Suk; Stamper, Lisa; Vilchez, Samuel; Velasquez, Daniel E; Moon, Sung-Sil; Hudgens, Michael G; Jiang, Baoming; Permar, Sallie R.
Afiliação
  • Becker-Dreps S; Department of Family Medicine, School of Medicine.
  • Choi WS; Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill.
  • Stamper L; Department of Pediatrics, Human Vaccine Institute, Duke University, Durham, North Carolina.
  • Vilchez S; Department of Microbiology and Parasitology, Faculty of Medical Sciences, National Autonomous University of Nicaragua, León.
  • Velasquez DE; Gastroenteritis and Respiratory Viruses Laboratory Branch, Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.
  • Moon SS; Gastroenteritis and Respiratory Viruses Laboratory Branch, Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.
  • Hudgens MG; Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill.
  • Jiang B; Gastroenteritis and Respiratory Viruses Laboratory Branch, Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.
  • Permar SR; Department of Pediatrics, Human Vaccine Institute, Duke University, Durham, North Carolina.
J Pediatric Infect Dis Soc ; 6(1): 87-90, 2017 Mar 01.
Article em En | MEDLINE | ID: mdl-26582774
To better understand underlying causes of lower rotavirus vaccine effectiveness in low-middle income countries (LMICs), we measured innate antiviral factors in Nicaraguan mothers' milk and immune response to the first dose of the pentavalent rotavirus vaccine in corresponding infants. No relationship was found between concentrations of innate factors and rotavirus vaccine response.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vacina Antipólio de Vírus Inativado / Vacina contra Difteria, Tétano e Coqueluche / Vacinas Anti-Haemophilus / Imunidade Inata / Leite Humano Tipo de estudo: Risk_factors_studies Limite: Female / Humans / Infant / Male País/Região como assunto: America central / Nicaragua Idioma: En Revista: J Pediatric Infect Dis Soc Ano de publicação: 2017 Tipo de documento: Article País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vacina Antipólio de Vírus Inativado / Vacina contra Difteria, Tétano e Coqueluche / Vacinas Anti-Haemophilus / Imunidade Inata / Leite Humano Tipo de estudo: Risk_factors_studies Limite: Female / Humans / Infant / Male País/Região como assunto: America central / Nicaragua Idioma: En Revista: J Pediatric Infect Dis Soc Ano de publicação: 2017 Tipo de documento: Article País de publicação: Reino Unido