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Improvement of bone repair in diabetic rats subjected to ƛ780 nm low-level laser therapy.
Nascimento, Marismar Fernandes do; Almeida, Bernadeth Moda de; Cunha, John Lennon Silva; Valois, Rafael Barreto Vieira; Pinheiro, Juliana Campos; Ribeiro, Maria Amália Gonzaga; Lima, Sonia Oliveira; Albuquerque-Júnior, Ricardo Luiz Cavalcanti de.
Afiliação
  • Nascimento MF; Universidade Tiradentes, Aracaju, SE, Brazil.
  • Almeida BM; Universidade Tiradentes, Aracaju, SE, Brazil.
  • Cunha JL; UNIT, Aracaju, SE, Brazil.
  • Valois RB; UNIT, Aracaju, SE, Brazil.
  • Pinheiro JC; UNIT, Aracaju, SE, Brazil.
  • Ribeiro MA; Department of Dentistry, Universidade Federal de Sergipe, Aracaju, SE, Brazil.
  • Lima SO; Department of Medicine, UNIT, Aracaju, SE, Brazil.
  • Albuquerque-Júnior RL; Department of Medicine, UNIT, Aracaju, SE, Brazil.
Acta Cir Bras ; 30(10): 660-7, 2015 Oct.
Article em En | MEDLINE | ID: mdl-26560423
PURPOSE: To investigate the effect of low-level laser therapy on bone healing in diabetic rats. METHODS: Bone cavities (19 mm diameter) were performed in the femur of 72 alloxan-induced diabetic rats, which were assigned into four groups: CTR (non-diabetic control), DBT (diabetic) CTRL (non-diabetic irradiated) and DBTL (diabetic irradiated). Low-level laser therapy was performed every 48 h for seven days. Animals were euthanized at seven, 18 and 30 days. Alkaline phosphatase serum levels and bone repair were analyzed. RESULTS: Low-level laser therapy significantly increased alkaline phosphatase in at seven and 18 days (p<0.001), and improved bone healing at seven (p<0.01), 18 (p<0.05) and 30 (p<0.01) in diabetic animals. In addition, bone healing in irradiated diabetic group was statistically similar to control group at 30 days (p>0.05). CONCLUSION: Low-level laser therapy increased the serum levels of alkaline phosphatase and improved bone healing in alloxan-induced diabetic rats.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Regeneração Óssea / Consolidação da Fratura / Terapia com Luz de Baixa Intensidade / Diabetes Mellitus Experimental / Lasers Semicondutores Tipo de estudo: Evaluation_studies Limite: Animals Idioma: En Revista: Acta Cir Bras Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Regeneração Óssea / Consolidação da Fratura / Terapia com Luz de Baixa Intensidade / Diabetes Mellitus Experimental / Lasers Semicondutores Tipo de estudo: Evaluation_studies Limite: Animals Idioma: En Revista: Acta Cir Bras Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil