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Detection of Bordetella pertussis using a PCR test in infants younger than one year old hospitalized with whooping cough in five Peruvian hospitals.
Castillo, María Esther; Bada, Carlos; Del Aguila, Olguita; Petrozzi-Helasvuo, Verónica; Casabona-Ore, Verónica; Reyes, Isabel; Del Valle-Mendoza, Juana.
Afiliação
  • Castillo ME; Instituto Nacional de Salud del Niño, Breña, Lima, Peru.
  • Bada C; Hospital de Emergencias Pediátricas, La Victoria, Lima, Peru.
  • Del Aguila O; Hospital Edgardo Rebagliati Martins, Jr, Jesús María, Lima, Peru.
  • Petrozzi-Helasvuo V; Centro de Investigación de la Facultad de Ciencias de la Salud, Universidad Peruana de Ciencias Aplicadas, Av. San Marcos cuadra 2, Chorrillos, Lima, Peru.
  • Casabona-Ore V; Centro de Investigación de la Facultad de Ciencias de la Salud, Universidad Peruana de Ciencias Aplicadas, Av. San Marcos cuadra 2, Chorrillos, Lima, Peru.
  • Reyes I; Hospital de Emergencias Pediátricas, La Victoria, Lima, Peru.
  • Del Valle-Mendoza J; Centro de Investigación de la Facultad de Ciencias de la Salud, Universidad Peruana de Ciencias Aplicadas, Av. San Marcos cuadra 2, Chorrillos, Lima, Peru. Electronic address: jdelvall@upc.edu.pe.
Int J Infect Dis ; 41: 36-41, 2015 Dec.
Article em En | MEDLINE | ID: mdl-26523641
OBJECTIVES: To report the incidence, epidemiology, and clinical features of Bordetella pertussis in Peruvian infants under 1 year old. PATIENTS AND METHODS: A prospective cross-sectional study was conducted in five hospitals in Peru from January 2010 to July 2012. A total of 392 infants under 1 year old were admitted with a clinical diagnosis of whooping cough and tested for B. pertussis by PCR. RESULTS: The pertussis toxin and IS481 genes were detected in 39.54% (155/392) of the cases. Infants aged less than 3 months were the most affected, with a prevalence of 73.55% (114/155). The most common household contact was the mother, identified in 20% (31/155) of cases. Paroxysm of coughing (89.03%, 138/155), cyanosis (68.39%, 106/155), respiratory distress (67.09%, 104/155), and breastfeeding difficulties (39.35%, 61/155) were the most frequent symptoms reported. CONCLUSION: An increase in pertussis cases has been reported in recent years in Peru, despite national immunization efforts. Surveillance with PCR for B. pertussis is essential, especially in infants less than 1 year old, in whom a higher rate of disease-related complications and higher mortality have been reported.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bordetella pertussis / Coqueluche Tipo de estudo: Diagnostic_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Infant / Male / Newborn País/Região como assunto: America do sul / Peru Idioma: En Revista: Int J Infect Dis Assunto da revista: DOENCAS TRANSMISSIVEIS Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Peru País de publicação: Canadá
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bordetella pertussis / Coqueluche Tipo de estudo: Diagnostic_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Infant / Male / Newborn País/Região como assunto: America do sul / Peru Idioma: En Revista: Int J Infect Dis Assunto da revista: DOENCAS TRANSMISSIVEIS Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Peru País de publicação: Canadá