Community-acquired Legionnaires' disease.
Semin Respir Infect
; 4(1): 32-9, 1989 Mar.
Article
em En
| MEDLINE
| ID: mdl-2652233
Legionellae are ubiquitous aquatic organisms. They are unique among the agents commonly responsible for bacterial pneumonia in humans in that they are not part of the normal human flora but are acquired from environmental sources. Prospective studies have shown that legionellae consistently rank among the top three bacteria as etiologic agents of community-acquired pneumonia. The clinical presentation of Legionnaires' disease is not distinguishable from that of other bacterial pneumonias. Culture of respiratory secretions using selective media, combined with one or more rapid diagnostic methods (direct fluorescent antibody staining, radiolabelled DNA probe, or urinary antigen detection) provides a specific diagnosis in the vast majority of cases. Sporadic cases have been linked to legionella colonization of water systems in homes and the work setting. Antibiotics commonly used in the therapy of community-acquired pneumonias, such as beta-lactam agents, are ineffective. Specific therapy with erythromycin reduces mortality to less than 10%.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doença dos Legionários
Tipo de estudo:
Etiology_studies
/
Observational_studies
Limite:
Humans
/
Middle aged
Idioma:
En
Revista:
Semin Respir Infect
Ano de publicação:
1989
Tipo de documento:
Article
País de publicação:
Estados Unidos