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Investigation of neutrophil-to-lymphocyte ratio and mean platelet volume in sudden hearing loss.
Kum, Rauf Oguzhan; Ozcan, Muge; Baklaci, Deniz; Yurtsever Kum, Nurcan; Yilmaz, Yavuz Fuat; Unal, Adnan; Avci, Yonca.
Afiliação
  • Kum RO; Ankara Numune Education and Research Hospital ENT Clinic, Ankara, Turkey. Electronic address: adigerok@yahoo.com.tr.
  • Ozcan M; Ankara Numune Education and Research Hospital ENT Clinic, Ankara, Turkey.
  • Baklaci D; Ankara Numune Education and Research Hospital ENT Clinic, Ankara, Turkey.
  • Yurtsever Kum N; Ankara Numune Education and Research Hospital ENT Clinic, Ankara, Turkey.
  • Yilmaz YF; Ankara Numune Education and Research Hospital ENT Clinic, Ankara, Turkey.
  • Unal A; Department of Otorhinolaryngology, Hitit University, Çorum, Turkey.
  • Avci Y; Ankara Numune Education and Research Hospital ENT Clinic, Ankara, Turkey.
Braz J Otorhinolaryngol ; 81(6): 636-41, 2015.
Article em En | MEDLINE | ID: mdl-26480902
INTRODUCTION: Several theories attempt to explain the pathophysiology of sudden hearing loss. OBJECTIVE: The objective of this study was to investigate the possible role of inflammation and atherothrombosis in sudden hearing loss patients through the neutrophil-to-lymphocyte ratio and mean platelet volume. METHODS: Study design - retrospective cross-sectional historical cohort. This study was conducted on two groups: one with 59 individuals diagnosed with sudden hearing loss, and other with 59 healthy individuals with the same characteristics of gender and age distribution, neutrophil-to-lymphocyte ratio and mean platelet volume levels were measured in patients diagnosed with sudden hearing loss as well as in the control group, and it was verified whether these results interfered for a better or worse prognosis with treatment of sudden deafness. RESULTS: Neutrophil-to-lymphocyte ratio levels are much higher in patients diagnosed with sudden hearing loss compared to the control group. Similarly, mean levels of neutrophil-to-lymphocyte ratio are higher in non-recovered versus recovered patients (p=0.001). However, we could not find a correlation with mean platelet volume levels (p>0.05). CONCLUSION: Neutrophil-to-lymphocyte ratio is a quick and reliable indicator regarding diagnosis and prognosis of sudden hearing loss; on the other hand, mean platelet volume may be considered a less important indicator in this aspect.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos / Perda Auditiva Súbita / Neutrófilos Tipo de estudo: Observational_studies / Prevalence_studies / Prognostic_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Braz J Otorhinolaryngol Assunto da revista: OTORRINOLARINGOLOGIA Ano de publicação: 2015 Tipo de documento: Article País de publicação: Brasil
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos / Perda Auditiva Súbita / Neutrófilos Tipo de estudo: Observational_studies / Prevalence_studies / Prognostic_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Braz J Otorhinolaryngol Assunto da revista: OTORRINOLARINGOLOGIA Ano de publicação: 2015 Tipo de documento: Article País de publicação: Brasil