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The Glasgow Prognostic Score. An useful tool to predict survival in patients with advanced esophageal squamous cell carcinoma.
Henry, Maria Aparecida Coelho de Arruda; Lerco, Mauro Masson; de Oliveira, Walmar Kerche; Guerra, Anderson Roberto; Rodrigues, Maria Aparecida Marchesan.
Afiliação
  • Henry MA; Botucatu Medical School, Universidade Estadual Paulista, BR.
  • Lerco MM; Medical School, UNESP, Botucatu, SP, BR.
  • de Oliveira WK; Medical School, UNESP, Botucatu, SP, BR.
  • Guerra AR; Botucatu Medical School, UNESP, Botucatu, SP, BR.
  • Rodrigues MA; Department of Pathology, Botucatu Medical School, UNESP, Botucatu, SP, BR.
Acta Cir Bras ; 30(8): 580-5, 2015 Aug.
Article em En | MEDLINE | ID: mdl-26352339
PURPOSE: To evaluate the usefulness of the Glasgow Prognostic Score (GPS) in patients with esophageal carcinoma (EC). METHODS: A total of 50 patients with EC were analyzed for GPS, nutritional and clinicopathologic parameters. Patients with CRP ≤ 1.0mg/L and albumin ≥ 3.5mg/L were considered as GPS = 0. Patients with only CRP increased or albumin decreased were classified as GPS = 1 and patients with CRP > 1.0mg/L and albumin < 3.5mg/L were considered as GPS = 2. RESULTS: GPS of 0, 1 and 2 were observed in seven, 23 and 20 patients, respectively. A significant inverse relationship was observed between GPS scores and the survival rate. The survival rate was greatest in patients with GPS = 0 and significantly higher than those from patients with GPS = 1 and GPS = 2. Minimum 12-month survival was observed in 71% patients with GPS = 0 and in 30% patients with GPS = 1. None of the patients with GPS = 2 survived for 12 months. A significant relationship between CRP or albumin individually and the survival rate was observed. No significant relationship among nutritional, clinic pathological parameters and survival was found. CONCLUSION: Glasgow Prognostic Score is an useful tool to predict survival in patients with esophageal carcinoma.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteína C-Reativa / Albumina Sérica / Neoplasias Esofágicas / Carcinoma de Células Escamosas Tipo de estudo: Evaluation_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Acta Cir Bras Ano de publicação: 2015 Tipo de documento: Article País de publicação: Brasil

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteína C-Reativa / Albumina Sérica / Neoplasias Esofágicas / Carcinoma de Células Escamosas Tipo de estudo: Evaluation_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Acta Cir Bras Ano de publicação: 2015 Tipo de documento: Article País de publicação: Brasil