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Impact of adherence to GOLD guidelines on 6-minute walk distance, MRC dyspnea scale score, lung function decline, quality of life, and quality-adjusted life years in a Shanghai suburb.
Jiang, Y Q; Zhu, Y X; Chen, X L; Xu, X; Li, F; Fu, H J; Shen, C Y; Lu, Y Y; Zhuang, Q J; Xu, G; Cai, Y Y; Zhang, Y; Liu, S S; Zhu, M Y; Li, S H.
Afiliação
  • Jiang YQ; Shanghai Municipal First People's Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China.
  • Zhu YX; Songjiang Branch of Shanghai Municipal First People's Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China.
  • Chen XL; Songjiang Branch of Shanghai Municipal First People's Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China.
  • Xu X; Songjiang Branch of Shanghai Municipal First People's Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China.
  • Li F; Songjiang Branch of Shanghai Municipal First People's Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China.
  • Fu HJ; Xiaokunshan Town Primary Care of Songjiang District, Shanghai, China.
  • Shen CY; Xiaokunshan Town Primary Care of Songjiang District, Shanghai, China.
  • Lu YY; Xiaokunshan Town Primary Care of Songjiang District, Shanghai, China.
  • Zhuang QJ; Xinbang Town Primary Care of Songjiang District, Shanghai, China.
  • Xu G; School of Public Health, Shanghai Jiao Tong University, Shanghai, China.
  • Cai YY; Institute of Respiratory Disease, Zhongshan Hospital Affiliated to Fudan University, Shanghai, China.
  • Zhang Y; Shanghai Songjiang District Public Health Bureau, Shanghai, China.
  • Liu SS; Shanghai Songjiang District Center for Diseases Control and Prevention, Shanghai, China.
  • Zhu MY; Shanghai Songjiang District Center for Diseases Control and Prevention, Shanghai, China.
  • Li SH; Songjiang Branch of Shanghai Municipal First People's Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China.
Genet Mol Res ; 14(3): 8861-70, 2015 Aug 03.
Article em En | MEDLINE | ID: mdl-26345817
We performed a 1-year cluster-randomized field trial to assess the effect of standardized management of chronic obstructive pulmonary disease (COPD) on lung function and quality of life (QOL) measures in patients in China. We used the Global Initiative for Chronic Obstructive Lung Disease (GOLD) treatment guidelines and assessed indexes including pulmonary function, QOL, quality-adjusted life years (QALY), Medical Research Council (MRC) dyspnea scale, 6-min walk distance (6-MWD), number of emergency visits, and frequency of hospitalization. Of a total of 711 patients with chronic cough and asthma, 132 were diagnosed as having COPD and 102 participated in this study [intervention group (N = 47); control group (N = 55)]. We found that adherence to GOLD guidelines had a perceivable impact on 6-MWD, MRC dyspnea scale score, and QOL. The average QALY increased by 1.42/person/year in the intervention group, but declined by 0.95/person/year in the control group. We conclude that standardized management improves disease severity, QOL, and QALY in COPD patients when treatment protocols adhere to GOLD guidelines.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Caminhada / Doença Pulmonar Obstrutiva Crônica Tipo de estudo: Clinical_trials / Diagnostic_studies / Guideline / Observational_studies Aspecto: Patient_preference Limite: Aged / Female / Humans / Male / Middle aged País/Região como assunto: Asia Idioma: En Revista: Genet Mol Res Assunto da revista: BIOLOGIA MOLECULAR / GENETICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: China País de publicação: Brasil

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Caminhada / Doença Pulmonar Obstrutiva Crônica Tipo de estudo: Clinical_trials / Diagnostic_studies / Guideline / Observational_studies Aspecto: Patient_preference Limite: Aged / Female / Humans / Male / Middle aged País/Região como assunto: Asia Idioma: En Revista: Genet Mol Res Assunto da revista: BIOLOGIA MOLECULAR / GENETICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: China País de publicação: Brasil