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Natural rubber latex coated with calcium phosphate for biomedical application.
Borges, Felipe Azevedo; Filho, Edson de Almeida; Miranda, Matheus Carlos Romeiro; Dos Santos, Márcio Luiz; Herculano, Rondinelli Donizetti; Guastaldi, Antônio Carlos.
Afiliação
  • Borges FA; a Biochemistry & Chemistry Technology Department - IQ , São Paulo State University , Araraquara , SP , Brazil.
  • Filho Ede A; b Physical Chemistry Department - IQ , São Paulo State University , Araraquara , SP , Brazil.
  • Miranda MC; a Biochemistry & Chemistry Technology Department - IQ , São Paulo State University , Araraquara , SP , Brazil.
  • Dos Santos ML; c Bioprocess & Biotechnology Department - FCF , São Paulo State University , Araraquara , SP , Brazil.
  • Herculano RD; b Physical Chemistry Department - IQ , São Paulo State University , Araraquara , SP , Brazil.
  • Guastaldi AC; c Bioprocess & Biotechnology Department - FCF , São Paulo State University , Araraquara , SP , Brazil.
J Biomater Sci Polym Ed ; 26(17): 1256-68, 2015.
Article em En | MEDLINE | ID: mdl-26307406
Natural rubber latex (NRL) is a flexible biomembrane that possesses angiogenic properties and has recently been used for guided bone regeneration, enhancing healing without fibrous tissue, allergies or rejection. Calcium phosphate (Ca/P) ceramics have chemical, biological, and mechanical properties similar to mineral phase of bone, and ability to bond to the host tissue, although it can disperse from where it is applied. Therefore, to create a composite that could enhance the properties of both materials, NRL biomembranes were coated with Ca/P. NRL biomembranes were soaked in 1.5 times concentrated SBF solution for seven days, avoiding the use of high temperatures. SEM showed that Ca/P has been coated in NRL biomembrane, XRD showed low crystallinity and FTIR showed that is the carbonated type B. Furthermore, hemolysis of erythrocytes, quantified spectrophotometrically using materials (Ca/P, NRL, and NRL + Ca/P) showed no hemolytic effects up to 0.125 mg/mL (compounds and mixtures), indicating no detectable disturbance of the red blood cell membranes. The results show that the biomimetic is an appropriate method to coat NRL with Ca/P without using high temperatures, aiming a new biomembrane to improve guided bone regeneration.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfatos de Cálcio / Materiais Revestidos Biocompatíveis / Látex Limite: Humans Idioma: En Revista: J Biomater Sci Polym Ed Assunto da revista: ENGENHARIA BIOMEDICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfatos de Cálcio / Materiais Revestidos Biocompatíveis / Látex Limite: Humans Idioma: En Revista: J Biomater Sci Polym Ed Assunto da revista: ENGENHARIA BIOMEDICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido