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Repeat pregnancy in women with HIV infection in Latin America and the Caribbean.
Kreitchmann, Regis; Megazzini, Karen; Melo, Victor Hugo; Fernandes Coelho, Débora; Watts, D Heather; Krauss, Margot; Gouvea, Maria Isabel; Duarte, Geraldo; Losso, Marcelo H; Siberry, George K.
Afiliação
  • Kreitchmann R; a Irmandade da Santa Casa de Misericordia de Porto Alegre , Professor Annes Dias 285, Porto Alegre , RS 90020090 , Brazil.
  • Megazzini K; b Westat , 1600 Research Blvd, Rockville , MD 20850 , USA.
  • Melo VH; c School of Medicine , Federal University of Minas Gerais , Av. Alfredo Balena 190, 2th floor, Belo Horizonte , Brazil.
  • Fernandes Coelho D; a Irmandade da Santa Casa de Misericordia de Porto Alegre , Professor Annes Dias 285, Porto Alegre , RS 90020090 , Brazil.
  • Watts DH; d U.S. Department of State , Washington , DC , USA.
  • Krauss M; b Westat , 1600 Research Blvd, Rockville , MD 20850 , USA.
  • Gouvea MI; e Hospital Federal dos Servidores do Estado , Rua Sacadura Cabral, 178, Anexo IV, 4 andar, Rio de Janeiro , RJ - CEP 20221903 , Brazil.
  • Duarte G; f Faculty of Medicine of Ribeirão Preto , University of São Paulo , Avenida Bandeirantes 3900, Ribeirão Preto, São Paulo , Brazil.
  • Losso MH; g HIV Unit , Hospital General de Agudos Jose Maria Ramos Mejia , Urquiza 609, Pabellon de Clinicas, 2 Piso, C1221ADC Buenos Aires , Argentina.
  • Siberry GK; h Maternal Pediatric Infectious Disease (MPID) Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) , National Institutes of Health , 6100 Executive Blvd., Room 4B11H, Bethesda , MD 20892-7510 , USA.
AIDS Care ; 27(10): 1289-97, 2015.
Article em En | MEDLINE | ID: mdl-26288031
Intended and unintended pregnancies occur frequently among human immunodeficiency virus (HIV)-infected women. We evaluated the occurrence of repeat pregnancy and characteristics associated with this outcome among HIV-infected women in Latin America and the Caribbean who were participating in the National Institute of Child Health and Human Development (NICHD) International Site Development Initiative (NISDI). Of the 1342 HIV-infected pregnant women enrolled in NISDI, 124 (9.2%) had one or more repeat pregnancies on study. Median time between the index delivery and date of conception of the subsequent pregnancy was 1.4 years (range 0.1-5.7). Younger age (odds ratio [OR] = 1.07, 95% confidence interval [CI]: 1.04-1.11 per one year decrease in age), hospitalization during the index pregnancy or up to six months post-partum [OR = 2.0, 95% CI: 1.2-3.4], and poor index pregnancy outcome (stillbirth or spontaneous/therapeutic abortion; OR = 3.4, 95% CI: 1.4-8.4) were associated with increased occurrence of repeat pregnancy in multivariable analysis. Among women with repeat pregnancies, the proportion receiving antiretroviral treatment (vs. prophylaxis) increased from 39.4% at the time of the index pregnancy to 81.8% at the time of the repeat pregnancy (p < 0.001). These results can help identify women most likely to benefit from reproductive counseling in order to assist with healthy pregnancy planning and prevention of unintended pregnancies.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Complicações Infecciosas na Gravidez / Infecções por HIV / Gravidez não Planejada Tipo de estudo: Prognostic_studies Limite: Adolescent / Adult / Female / Humans / Pregnancy Idioma: En Revista: AIDS Care Assunto da revista: SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS) Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Complicações Infecciosas na Gravidez / Infecções por HIV / Gravidez não Planejada Tipo de estudo: Prognostic_studies Limite: Adolescent / Adult / Female / Humans / Pregnancy Idioma: En Revista: AIDS Care Assunto da revista: SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS) Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido