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Immediate tooth replantation in rats: effect of systemic antibiotic therapy with amoxicillin and tetracycline.
Melo, Moriel Evangelista; Silva, Cristina Antoniali; de Souza Gomes, Weglis Dyanne; da Silva, Vanessa Ferreira; Brandini, Daniela Atili; Poi, Wilson Roberto; Castilho, Lithiene Ribeiro; Sonoda, Celso Koogi; Panzarini, Sônia Regina.
Afiliação
  • Melo ME; Department of Surgery and Integrated Clinics, School of Dentistry of Araçatuba, UNESP -Univ Estadual Paulista, Araçatuba, São Paulo, Brazil.
  • Silva CA; Department of Surgery and Integrated Clinics, School of Dentistry of Araçatuba, UNESP -Univ Estadual Paulista, Araçatuba, São Paulo, Brazil.
  • de Souza Gomes WD; Department of Surgery and Integrated Clinics, School of Dentistry of Araçatuba, UNESP -Univ Estadual Paulista, Araçatuba, São Paulo, Brazil.
  • da Silva VF; Department of Surgery and Integrated Clinics, School of Dentistry of Araçatuba, UNESP -Univ Estadual Paulista, Araçatuba, São Paulo, Brazil.
  • Brandini DA; Department of Surgery and Integrated Clinics, School of Dentistry of Araçatuba, UNESP -Univ Estadual Paulista, Araçatuba, São Paulo, Brazil.
  • Poi WR; Department of Surgery and Integrated Clinics, School of Dentistry of Araçatuba, UNESP -Univ Estadual Paulista, Araçatuba, São Paulo, Brazil.
  • Castilho LR; Department of Surgery and Integrated Clinics, School of Dentistry of Araçatuba, UNESP -Univ Estadual Paulista, Araçatuba, São Paulo, Brazil.
  • Sonoda CK; Department of Surgery and Integrated Clinics, School of Dentistry of Araçatuba, UNESP -Univ Estadual Paulista, Araçatuba, São Paulo, Brazil.
  • Panzarini SR; Department of Surgery and Integrated Clinic, Discipline of Integrated Clinic, School of Dentistry of Araçatuba, UNESP -Univ Estadual Paulista, Rua José Bonifácio 1193, CEP, 1601-050, Araçatuba, São Paulo, Brazil. panzarin@foa.unesp.br.
Clin Oral Investig ; 20(3): 523-32, 2016 Apr.
Article em En | MEDLINE | ID: mdl-26205067
OBJECTIVES: The aim of this study was to evaluate the influence of systemic administration of antibiotics (amoxicillin and tetracycline) at the different phases of the repair process (7, 15, 30 days) in immediate rat tooth replantation. MATERIALS AND METHODS: Ninety rats had their incisors extracted and stored in saline for 5 min. Next, the teeth were replanted, and the animals were assigned to three groups according to the antibiotic administered by oral gavage: control group, amoxycillin group, and tetracycline group. Euthanasia was performed at 7, 15, and 30 days after replantation. RESULTS: Regardless of the evaluation period, the connective tissue underlying the epithelial attachment and the periodontal ligament showed statistically significant difference relative to the acute inflammatory infiltrate, which was more intense in the control group followed by the tetracycline group. CONCLUSION: These results point to the fact that systemic antibiotic therapy (SAT) in immediate tooth replantation is beneficial to pulpal and periodontal ligament repair and that amoxycillin is an excellent option. CLINICAL RELEVANCE: There is a lack of randomized studies assessing how the use of systemic antibiotics could influence tooth healing after immediate replantation.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ligamento Periodontal / Tetraciclina / Reimplante Dentário / Inserção Epitelial / Amoxicilina / Incisivo Limite: Animals Idioma: En Revista: Clin Oral Investig Assunto da revista: ODONTOLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Brasil País de publicação: Alemanha
Texto completo
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Imprimir
XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ligamento Periodontal / Tetraciclina / Reimplante Dentário / Inserção Epitelial / Amoxicilina / Incisivo Limite: Animals Idioma: En Revista: Clin Oral Investig Assunto da revista: ODONTOLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Brasil País de publicação: Alemanha