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Investigation of TG gene variants and their effects on growth, carcass composition, and meat quality traits in Chinese steers.
Zhang, L P; Gan, Q F; Hou, G Y; Gao, H J; Li, J Y; Xu, S Z.
Afiliação
  • Zhang LP; Key Laboratory for Farm Animal Genetic Resources and Utilization of Ministry of Agriculture of China, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China.
  • Gan QF; College of Animal Science, Fujian Agricultural and Forestry University, Fuzhou, Fujian, China.
  • Hou GY; Institute of Tropical Crop Genetic Resources, Chinese Academy of Tropical Agricultural Sciences, Danzhou, Hainan, China.
  • Gao HJ; Key Laboratory for Farm Animal Genetic Resources and Utilization of Ministry of Agriculture of China, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China.
  • Li JY; Key Laboratory for Farm Animal Genetic Resources and Utilization of Ministry of Agriculture of China, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China JL1@iascaas.net.cn.
  • Xu SZ; Key Laboratory for Farm Animal Genetic Resources and Utilization of Ministry of Agriculture of China, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China.
Genet Mol Res ; 14(2): 5320-6, 2015 May 22.
Article em En | MEDLINE | ID: mdl-26125728
Thyroid hormones play an important role in regulating metabolism and can affect metabolism-related traits such as fat deposition. The thyroglobulin (TG) gene produces the precursor of thyroid hormones and has been proposed as a candidate gene for a quantitative trait locus with an effect on fat deposition. In this study, we identified 4 novel single nucleotide polymorphisms (SNPs) in the 5' flanking region of the TG gene using a DNA sequencing method. The SNP marker association analysis indicated that the T1355C SNPs were significantly associated with meat percentage (P < 0.05). A significant association between the G1356A polymorphism and live weight and loin muscle area was also detected (P < 0.05). However, no significant association was found between 4 SNPs and the other growth, carcass composition, and meat quality traits including intramuscular fat. The results of this study suggest that TG gene-specific SNPs may be a useful marker for growth traits in marker-assisted selection programs in beef cattle.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tireoglobulina / Polimorfismo de Nucleotídeo Único / Locos de Características Quantitativas / Estudos de Associação Genética Tipo de estudo: Prognostic_studies Limite: Animals País/Região como assunto: Asia Idioma: En Revista: Genet Mol Res Assunto da revista: BIOLOGIA MOLECULAR / GENETICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: China País de publicação: Brasil
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tireoglobulina / Polimorfismo de Nucleotídeo Único / Locos de Características Quantitativas / Estudos de Associação Genética Tipo de estudo: Prognostic_studies Limite: Animals País/Região como assunto: Asia Idioma: En Revista: Genet Mol Res Assunto da revista: BIOLOGIA MOLECULAR / GENETICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: China País de publicação: Brasil