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Antifungal activity of extracts and isolated compounds from Buchenavia tomentosa on Candida albicans and non-albicans.
Teodoro, Guilherme R; Brighenti, Fernanda L; Delbem, Alberto C Botazzo; Delbem, Ádina Cléia B; Khouri, Sonia; Gontijo, Aline Vidal L; Pascoal, Aislan Crf; Salvador, Marcos J; Koga-Ito, Cristiane Y.
Afiliação
  • Teodoro GR; Oral Biopathology Graduate Program, São José dos Campos Institute of Science & Technology, Universidade Estadual Paulista/UNESP, São Paulo, Brazil.
  • Brighenti FL; Department of Orthodontics & Pediatric Dentistry, Araraquara Dental School, Universidade Estadual Paulista (UNESP), São Paulo, Brazil.
  • Delbem AC; Department of Pediatric Dentistry, Araçatuba Dental School, Universidade Estadual Paulista (UNESP), São Paulo, Brazil.
  • Delbem ÁC; Department of Pediatric Dentistry, Araçatuba Dental School, Universidade Estadual Paulista (UNESP), São Paulo, Brazil.
  • Khouri S; Faculdade de Ciências da Saúde, Universidade do Vale do Paraíba (UNIVAP), São José dos Campos, São Paulo, Brazil.
  • Gontijo AV; Department of Environmental Engineering, São José dos Campos Institute of Science & Technology, Universidade Estadual Paulista/UNESP, São Paulo, Brazil.
  • Pascoal AC; Department of Plant Biology, PPGBTPB, Institute of Biology, Universidade Estadual de Campinas (UNICAMP), São Paulo, Brazil.
  • Salvador MJ; Department of Plant Biology, PPGBTPB, Institute of Biology, Universidade Estadual de Campinas (UNICAMP), São Paulo, Brazil.
  • Koga-Ito CY; Department of Plant Biology, PPGBTPB, Institute of Biology, Universidade Estadual de Campinas (UNICAMP), São Paulo, Brazil.
Future Microbiol ; 10(6): 917-27, 2015.
Article em En | MEDLINE | ID: mdl-26059616
AIM: This study aimed to evaluate the antifungal activity of Buchenavia tomentosa extract and bioactive compounds on six Candida species. MATERIALS & METHODS: The antimicrobial activity of extract was evaluated using standard strains and clinical isolates. Cytotoxicity was tested in order to evaluate cell damage caused by the extract. Extract was chemically characterized and the antifungal activity of its compounds was evaluated. RESULTS: Extract showed antifungal activity on Candida species. Candida non-albicans were more susceptible than Candida albicans. Low cytotoxicity for extract was observed. The isolated compounds presented antifungal activity at least against one Candida spp. and all compounds presented antifungal effect on Candida glabrata. CONCLUSION: Extracts from Buchenavia tomentosa showed promising antifungal activity on Candida species with low cytotoxicity. Gallic acid, corilagin and ellagic acid showed promising inhibitory activity on Candida glabrata.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Candida / Extratos Vegetais / Combretaceae / Antifúngicos Limite: Animals Idioma: En Revista: Future Microbiol Assunto da revista: MICROBIOLOGIA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Candida / Extratos Vegetais / Combretaceae / Antifúngicos Limite: Animals Idioma: En Revista: Future Microbiol Assunto da revista: MICROBIOLOGIA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido