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Clinical variables associated with disability in leprosy cases in northeast Brazil.
Santos, Victor Santana; de Matos, Andressa Mayara Santos; de Oliveira, Lorena Sheila Alves; de Lemos, Ligia Mara Dolce; Gurgel, Ricardo Queiroz; Reis, Francisco Prado; Santos, Vanessa Tavares de Gois; Feitosa, Vera Lúcia Corrêa.
Afiliação
  • Santos VS; Postgraduate Program in Health Sciences, Federal University of Sergipe, Brazil. santosvictor19@gmail.com.
J Infect Dev Ctries ; 9(3): 232-8, 2015 Mar 15.
Article em En | MEDLINE | ID: mdl-25771459
INTRODUCTION: The clinical outcomes of leprosy include complications such as physical disabilities and deformities that vary according to the degree of impairment of nerve trunks. Knowledge of the factors that lead to the development of these complications is important for disability prevention programs. This study aimed to evaluate clinical factors associated with the occurrence of physical disability in leprosy cases. METHODOLOGY: This was a retrospective study of 2,358 cases of leprosy in Aracaju, northeast Brazil, between 2001 and 2011. Analysis was done using the Chi-square test and logistic regression model. RESULTS: Significant factors associated with disability were found to be male gender, having more than two affected nerves, multibacillary leprosy classification, leprosy reaction, and lepromatous leprosy. The multivariate analysis revealed that the associated factors included having more than two affected nerves, leprosy reaction (adjusted odds ratio [aOR]: 2.02, 95% confidence interval [CI]: 1.36 to 3.01), the multibacillary form (aOR: 2.74, 95% CI: 1.84 to 4.08), and lepromatous leprosy (aOR: 4.87, 95% CI: 2.86 to 16.08). CONCLUSIONS: The number of affected nerves, leprosy reaction, operational classification, and clinical presentation were identified as the main factors associated with the development of disability in leprosy patients.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pessoas com Deficiência / Doenças Neurodegenerativas / Hanseníase Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Child / Female / Humans / Male / Middle aged País/Região como assunto: America do sul / Brasil Idioma: En Revista: J Infect Dev Ctries Assunto da revista: DOENCAS TRANSMISSIVEIS Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Brasil País de publicação: Itália
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pessoas com Deficiência / Doenças Neurodegenerativas / Hanseníase Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Child / Female / Humans / Male / Middle aged País/Região como assunto: America do sul / Brasil Idioma: En Revista: J Infect Dev Ctries Assunto da revista: DOENCAS TRANSMISSIVEIS Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Brasil País de publicação: Itália